Angiopoietin-2/Tie2 Complex Crystal Structure

Summary for 2GY7

Related2GY5 1Z3S
DescriptorAngiopoietin-2, Angiopoietin-1 receptor, CALCIUM ION, ... (6 entities in total)
Functional Keywordsreceptor-ligand complex, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationSecreted O15123
Membrane; Single-pass type I membrane protein Q02763
Total number of polymer chains2
Total molecular weight74161.74
Barton, W.A.,Nikolov, D.B. (deposition date: 2006-05-09, release date: 2006-06-06, Last modification date: 2011-07-13)
Primary citation
Barton, W.A.,Tzvetkova-Robev, D.,Miranda, E.P.,Kolev, M.V.,Rajashankar, K.R.,Himanen, J.P.,Nikolov, D.B.
Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex.
Nat.Struct.Mol.Biol., 13:524-532, 2006
PubMed: 16732286 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb1101
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.312348.8%9.3%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2gy7
no rotation
Molmil generated image of 2gy7
rotated about x axis by 90°
Molmil generated image of 2gy7
rotated about y axis by 90°