2AO7

Adam10 Disintegrin and cysteine- rich domain

Summary for 2AO7

DescriptorADAM 10, SULFATE ION (2 entities in total)
Functional Keywordsextracellular, protease, disintegrin, hydrolase
Biological sourceBos taurus (cattle)
Cellular locationGolgi apparatus membrane; Single-pass type I membrane protein Q10741
Total number of polymer chains1
Total molecular weight21062.79
Authors
Janes, P.W.,Saha, N.,Barton, W.A.,Kolev, M.V.,Wimmer-Kleikamp, S.H.,Nievergall, E.,Blobel, C.P.,Himanen, J.-P.,Lackmann, M.,Nikolov, D.B. (deposition date: 2005-08-12, release date: 2006-08-08, Last modification date: 2011-07-13)
Primary citation
Janes, P.W.,Saha, N.,Barton, W.A.,Kolev, M.V.,Wimmer-Kleikamp, S.H.,Nievergall, E.,Blobel, C.P.,Himanen, J.-P.,Lackmann, M.,Nikolov, D.B.
Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Cell(Cambridge,Mass.), 123:291-304, 2005
PubMed: 16239135 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2005.08.014
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.474202.9%5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2ao7
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Molmil generated image of 2ao7
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Molmil generated image of 2ao7
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 2ao7
no rotation
Molmil generated image of 2ao7
rotated about x axis by 90°
Molmil generated image of 2ao7
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2ao7.pdb1.gz [24.11 KB])
Coordinate files for Biological unit (2ao7.pdb2.gz [46.24 KB])