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PDB: 48 件
4V7G
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BU of 4v7g by Molmil
Crystal Structure of Lumazine Synthase from Bacillus Anthracis
分子名称: 6,7-dimethyl-8-ribityllumazine synthase, PHOSPHATE ION
著者Morgunova, E, Illarionov, B, Saller, S, Popov, A, Sambaiah, T, Bacher, A, Cushman, M, Fischer, M, Ladenstein, R.
登録日2009-09-16
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural study and thermodynamic characterization of inhibitor binding to lumazine synthase from Bacillus anthracis.
Acta Crystallogr.,Sect.D, 66, 2010
1OPO
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BU of 1opo by Molmil
THE STRUCTURE OF CARNATION MOTTLE VIRUS
分子名称: CALCIUM ION, Coat protein, SULFATE ION
著者Morgunova, E, Dauter, Z, Fry, E, Stuart, D, Stel'mashchuk, V, Mikhailov, A.M, Wilson, K.S, Vainshtein, B.K.
登録日2003-03-06
公開日2003-04-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The atomic structure of Carnation Mottle Virus capsid protein
Febs Lett., 338, 1994
5EGO
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BU of 5ego by Molmil
HOXB13-MEIS1 heterodimer bound to methylated DNA
分子名称: DNA (5'-D(*CP*CP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*TP*GP*TP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*GP*G)-3'), Homeobox protein Hox-B13, ...
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-27
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Science, 356, 2017
5EF6
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BU of 5ef6 by Molmil
Structure of HOXB13 complex with methylated DNA
分子名称: DNA (5'-D(P*GP*GP*AP*CP*CP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*GP*GP*TP*CP*C)-3'), Homeobox protein Hox-B13
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-23
公開日2017-02-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Science, 356, 2017
5HOD
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BU of 5hod by Molmil
Structure of LHX4 transcription factor complexed with DNA
分子名称: DNA (5'-D(P*AP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*CP*GP*TP*AP*AP*TP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*AP*TP*TP*AP*CP*GP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*T)-3'), LIM/homeobox protein Lhx4
著者Morgunova, E, Yin, Y, Popov, A, Taipale, J.
登録日2016-01-19
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.682 Å)
主引用文献Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Science, 356, 2017
6SJD
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BU of 6sjd by Molmil
ZC3H12B-ribonuclease domain bound to RNA
分子名称: CACODYLATE ION, MAGNESIUM ION, Probable ribonuclease ZC3H12B, ...
著者Morgunova, E, Bourenkov, G, Taipale, J.
登録日2019-08-13
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Binding specificities of human RNA-binding proteins toward structured and linear RNA sequences.
Genome Res., 30, 2020
3HI8
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BU of 3hi8 by Molmil
Crystal structure of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii
分子名称: Proliferating cell nuclear antigen PcnA
著者Morgunova, E, Gray, F.C, MacNeill, S.A, Ladenstein, R.
登録日2009-05-19
公開日2009-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.202 Å)
主引用文献Structural insights into the adaptation of proliferating cell nuclear antigen (PCNA) from Haloferax volcanii to a high-salt environment.
Acta Crystallogr.,Sect.D, 65, 2009
5BNG
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BU of 5bng by Molmil
monomer of TALE type homeobox transcription factor MEIS1 complexes with specific DNA
分子名称: DNA (5'-D(P*AP*AP*TP*TP*AP*GP*CP*TP*GP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*CP*AP*GP*CP*TP*AP*A)-3'), DNA (5'-D(P*TP*GP*AP*CP*AP*GP*CP*TP*AP*A-3'), ...
著者Morgunova, E, Jolma, A, Yin, Y, Nitta, K, Dave, K, Popov, A, Taipale, M, Enge, M, Kivioja, T, Taipale, J.
登録日2015-05-26
公開日2015-11-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献DNA-dependent formation of transcription factor pairs alters their binding specificity.
Nature, 527, 2015
8OSB
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BU of 8osb by Molmil
TWIST1-TCF4-ALX4 complex on specific DNA
分子名称: DNA (25-MER), Homeobox protein aristaless-like 4, Transcription factor 4, ...
著者Morgunova, E, Kim, S, Popov, A, Wysocka, J, Taipale, J.
登録日2023-04-18
公開日2024-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献DNA-guided transcription factor cooperativity shapes face and limb mesenchyme.
Cell, 187, 2024
5EG0
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BU of 5eg0 by Molmil
HOXB13-MEIS1 heterodimer bound to DNA
分子名称: DNA (5'-D(*CP*CP*TP*CP*GP*TP*AP*AP*AP*AP*CP*TP*GP*TP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*G)-3'), Homeobox protein Hox-B13, ...
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-26
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Molecular basis of recognition of two distinct DNA sequences by a single transcription factor
To Be Published
5EEA
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BU of 5eea by Molmil
Structure of HOXB13-DNA(CAA) complex
分子名称: DNA (5'-D(P*GP*GP*AP*CP*CP*CP*AP*AP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*TP*TP*GP*GP*GP*TP*CP*C)-3'), Homeobox protein Hox-B13
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-22
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.195 Å)
主引用文献Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Elife, 7, 2018
5EDN
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BU of 5edn by Molmil
Structure of HOXB13-DNA(TCG) complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(P*GP*GP*AP*CP*CP*TP*CP*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*GP*TP*CP*C)-3'), ...
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-21
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Elife, 7, 2018
2VI5
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BU of 2vi5 by Molmil
LUMAZINE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO N-6-(ribitylamino)pyrimidine-2,4(1H,3H)-dione-5-yl-propionamide
分子名称: 1-deoxy-1-{[(5S)-2,6-dioxo-5-(propanoylamino)-1,2,5,6-tetrahydropyrimidin-4-yl]amino}-D-ribitol, 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE, PHOSPHATE ION, ...
著者Morgunova, E, Zhang, Y, Jin, G, Illarionov, B, Bacher, A, Fischer, M, Cushman, M, Ladenstein, R.
登録日2007-11-27
公開日2008-04-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A New Series of N-[2,4-Dioxo-6-D-Ribitylamino-1,2, 3,4-Tetrahydropyrimidin-5-Yl]Oxalamic Acid Derivatives as Inhibitors of Lumazine Syntase and Riboflavin Synthase: Design, Synthesis, Biochemical Evaluation, Crystallography and Mechanistic Implications.
J.Org.Chem., 73, 2008
7Z5I
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BU of 7z5i by Molmil
Transcription factor MYF5 bound to symmetrical site
分子名称: DNA (5'-D(P*AP*CP*GP*CP*GP*TP*CP*AP*GP*CP*TP*GP*AP*CP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*CP*GP*TP*CP*AP*GP*CP*TP*GP*AP*CP*GP*CP*GP*T)-3'), Myogenic factor 5
著者Morgunova, E, Popov, A, Yin, Y, Taipale, J.
登録日2022-03-09
公開日2023-03-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Transcription factor MYF5 bound to symmetrical site
To Be Published
7Z5K
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BU of 7z5k by Molmil
Transcription factor MYF5 bound to non-symmetrical site
分子名称: DNA (5'-D(P*AP*CP*GP*CP*GP*TP*CP*AP*GP*CP*TP*GP*TP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*CP*AP*AP*CP*AP*GP*CP*TP*GP*AP*CP*GP*CP*GP*T)-3'), Myogenic factor 5
著者Morgunova, E, Popov, A, Yin, Y, Taipale, J.
登録日2022-03-09
公開日2023-03-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Transcription factor MYF5 bound to non-symmetrical site
To Be Published
8BYX
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BU of 8byx by Molmil
HOXB13-homodimer bound to DNA
分子名称: DNA, Homeobox protein Hox-B13
著者Morgunova, E, Popov, A, Yin, Y, Taipale, J.
登録日2022-12-14
公開日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献HOXB13-homodimer bound to DNA
To Be Published
8BZM
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BU of 8bzm by Molmil
FOXK1-ELF1-heterodimer bound to DNA
分子名称: DNA, ETS-related transcription factor Elf-1, Forkhead box protein K1, ...
著者Morgunova, E, Popov, A, Yin, Y, Taipale, J.
登録日2022-12-15
公開日2023-12-27
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献FOXK1-ELF1_heterodimer bound to DNA
To Be Published
6ES3
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BU of 6es3 by Molmil
Structure of CDX2-DNA(TCG)
分子名称: DNA (5'-D(P*GP*GP*AP*GP*GP*TP*CP*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*CP*GP*AP*CP*CP*TP*CP*C)-3'), Homeobox protein CDX-2
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2017-10-19
公開日2018-03-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Elife, 7, 2018
6ES2
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BU of 6es2 by Molmil
Structure of CDX2-DNA(CAA)
分子名称: DNA (5'-D(P*GP*GP*AP*GP*GP*CP*AP*AP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*TP*TP*GP*CP*CP*TP*CP*C)-3'), Homeobox protein CDX-2
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2017-10-19
公開日2018-03-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.
Elife, 7, 2018
1CK7
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BU of 1ck7 by Molmil
GELATINASE A (FULL-LENGTH)
分子名称: CALCIUM ION, CHLORIDE ION, PROTEIN (GELATINASE A), ...
著者Morgunova, E, Tuuttila, A, Bergmann, U, Isupov, M, Lindqvist, Y, Schneider, G, Tryggvason, K.
登録日1999-04-28
公開日1999-08-25
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed.
Science, 284, 1999
5LTY
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BU of 5lty by Molmil
Homeobox transcription factor CDX2 bound to methylated DNA
分子名称: DNA (5'-D(P*GP*GP*AP*GP*GP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*CP*CP*TP*CP*C)-3'), Homeobox protein CDX-2
著者Morgunova, E, Popov, A, Taipale, J.
登録日2016-09-07
公開日2017-05-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Science, 356, 2017
7PSX
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BU of 7psx by Molmil
Structure of HOXB13 bound to hydroxymethylated DNA
分子名称: DNA (5'-D(P*GP*GP*AP*CP*CP*TP*5HCP*AP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*GP*TP*CP*C)-3'), Homeobox protein Hox-B13, ...
著者Morgunova, E, Popov, A, Yin, Y, Taipale, J.
登録日2021-09-24
公開日2022-10-05
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of HOXB13 bound to hydroxymethylated DNA
To Be Published
7Q3O
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BU of 7q3o by Molmil
Structure of CDX1 bound to hydroxymethylated DNA
分子名称: Homeobox protein CDX-1, hydroxymethylated DNA (18-MER)
著者Morgunova, E, Yin, Y, Popov, A, Taipale, J.
登録日2021-10-28
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Structure of CDX1 bound to hydroxymethylated DNA
To Be Published
7Q4N
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BU of 7q4n by Molmil
transcription factor CDX2 bound to hydroxymethylated DNA
分子名称: DNA (18-MER), Homeobox protein CDX-2
著者Morgunova, E, Yin, Y, Popov, A, Taipale, J.
登録日2021-11-01
公開日2022-11-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献transcription factor CDX2 bound to hydroxymethylated DNA
To Be Published
5LUX
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BU of 5lux by Molmil
Homeobox transcription factor CDX1 bound to methylated DNA
分子名称: DNA (5'-D(P*GP*AP*GP*GP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*GP*GP*AP*GP*GP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*CP*CP*TP*C)-3'), ...
著者Morgunova, E, Popov, A, Taipale, J.
登録日2016-09-12
公開日2017-05-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Science, 356, 2017

 

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