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5EG0

HOXB13-MEIS1 heterodimer bound to DNA

Summary for 5EG0
Entry DOI10.2210/pdb5eg0/pdb
DescriptorHomeobox protein Meis2, DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*CP*GP*TP*AP*AP*AP*AP*CP*TP*GP*TP*CP*AP*AP*C)-3'), ... (5 entities in total)
Functional Keywordstranscription factor, heterodimer, complex, bound to dna, transcription
Biological sourceHomo sapiens (Human)
More
Cellular locationNucleus : O14770 Q92826
Total number of polymer chains4
Total formula weight25123.67
Authors
Morgunova, E.,Yin, Y.,Jolma, A.,Popov, A.,Taipale, J. (deposition date: 2015-10-26, release date: 2016-11-09, Last modification date: 2024-01-10)
Primary citationMorgunova, E.,Yin, Y.,Jolma, A.,Popov, A.,Taipale, J.
Molecular basis of recognition of two distinct DNA sequences by a single transcription factor
To Be Published,
Experimental method
X-RAY DIFFRACTION (3.101 Å)
Structure validation

218853

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