5BNG

monomer of TALE type homeobox transcription factor MEIS1 complexes with specific DNA

Summary for 5BNG

• Entry DOI: 10.2210/pdb5bng/pdb
• Descriptor: Homeobox protein Meis2, DNA (5'-D(P*TP*TP*AP*GP*CP*TP*GP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*CP*AP*GP*CP*TP*AP*A-3'), ... (6 entities in total)
• Functional Keywords: protein-dna complex, transcription factor, tale type homeobox protein, protein/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : O14770
• Total number of polymer chains: 6
• Total formula weight: 27695.28

Authors

Morgunova, E.,Jolma, A.,Yin, Y.,Nitta, K.,Dave, K.,Popov, A.,Taipale, M.,Enge, M.,Kivioja, T.,Taipale, J. (deposition date: 2015-05-26, release date: 2015-11-04, Last modification date: 2024-05-08)

• Primary citation: Jolma, A.,Yin, Y.,Nitta, K.R.,Dave, K.,Popov, A.,Taipale, M.,Enge, M.,Kivioja, T.,Morgunova, E.,Taipale, J.; DNA-dependent formation of transcription factor pairs alters their binding specificity.; Nature, 527:384-388, 2015; PubMed: 26550823; DOI: 10.1038/nature15518

Experimental method

X-RAY DIFFRACTION (3.5 Å)