6SJD

ZC3H12B-ribonuclease domain bound to RNA

Summary for 6SJD

• Entry DOI: 10.2210/pdb6sjd/pdb
• Descriptor: Probable ribonuclease ZC3H12B, RNA (5'-R(*UP*GP*CP*GP*AP*CP*AP*GP*UP*CP*GP*GP*UP*AP*GP*CP*A)-3'), MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: pin rnase domain, splice donor sequence rna, degradation of cytoplasmic viral and/or unspliced transcripts, rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 48559.30

Authors

Morgunova, E.,Bourenkov, G.,Taipale, J. (deposition date: 2019-08-13, release date: 2020-07-22, Last modification date: 2024-01-24)

• Primary citation: Jolma, A.,Zhang, J.,Mondragon, E.,Morgunova, E.,Kivioja, T.,Laverty, K.U.,Yin, Y.,Zhu, F.,Bourenkov, G.,Morris, Q.,Hughes, T.R.,Maher 3rd, L.J.,Taipale, J.; Binding specificities of human RNA-binding proteins toward structured and linear RNA sequences.; Genome Res., 30:962-973, 2020; PubMed: 32703884; DOI: 10.1101/gr.258848.119

Experimental method

X-RAY DIFFRACTION (3.29 Å)