5HOD

Structure of LHX4 transcription factor complexed with DNA

Summary for 5HOD

• Entry DOI: 10.2210/pdb5hod/pdb
• Descriptor: LIM/homeobox protein Lhx4, DNA (5'-D(P*AP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*CP*GP*TP*AP*AP*TP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*AP*TP*TP*AP*CP*GP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*T)-3'), ... (4 entities in total)
• Functional Keywords: transcription factor, complex with dna, dimer, transcription
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q969G2
• Total number of polymer chains: 4
• Total formula weight: 26593.65

Authors

Morgunova, E.,Yin, Y.,Popov, A.,Taipale, J. (deposition date: 2016-01-19, release date: 2017-02-01, Last modification date: 2024-01-10)

• Primary citation: Yin, Y.,Morgunova, E.,Jolma, A.,Kaasinen, E.,Sahu, B.,Khund-Sayeed, S.,Das, P.K.,Kivioja, T.,Dave, K.,Zhong, F.,Nitta, K.R.,Taipale, M.,Popov, A.,Ginno, P.A.,Domcke, S.,Yan, J.,Schubeler, D.,Vinson, C.,Taipale, J.; Impact of cytosine methylation on DNA binding specificities of human transcription factors.; Science, 356:-, 2017; PubMed: 28473536; DOI: 10.1126/science.aaj2239

Experimental method

X-RAY DIFFRACTION (2.682 Å)