5NG1
 
 | | TUBULIN-MTC-zampanolide complex | | 分子名称: | (2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamide, (2~{Z},4~{E})-~{N}-[(~{S})-oxidanyl-[(1~{S},2~{E},5~{S},11~{R},17~{S},19~{R})-3,11,19-trimethyl-7,13-bis(oxidanylidene)-6,21-dioxabicyclo[15.3.1]henicos-2-en-5-yl]methyl]hexa-2,4-dienamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | 著者 | Field, J.J, Pera, B, Estevez Gallego, J, Calvo, E, Rodriguez-Salarichs, J, Saez-Calvo, G, Zuwerra, D, Jordi, M, Prota, A.E, Menchon, G, Miller, J.H, Altmann, K.-H, Diaz, J.F. | | 登録日 | 2017-03-16 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites.
J. Nat. Prod., 81, 2018
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7TZ1
 | | Crystal Structure of a Mycobacteriophage Cluster A2 Immunity Repressor:DNA Complex | | 分子名称: | DNA (5'-D(P*CP*CP*CP*GP*CP*TP*TP*GP*AP*CP*AP*GP*CP*CP*AP*CP*CP*GP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*CP*GP*GP*TP*GP*GP*CP*TP*GP*TP*CP*AP*AP*GP*CP*GP*GP*G)-3'), Immunity repressor | | 著者 | McGinnis, R.J, Brambley, C.A, Stamey, B, Green, W.C, Gragg, K.N, Cafferty, E.R, Terwilliger, T.C, Hammel, M, Hollis, T.J, Miller, J.M, Gainey, M.D, Wallen, J.R. | | 登録日 | 2022-02-15 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence.
Nat Commun, 13, 2022
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4B3P
 | | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | | 分子名称: | DNA, P51 RT, REVERSE TRANSCRIPTASE/RIBONUCLEASE H, ... | | 著者 | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | | 登録日 | 2012-07-25 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (4.839 Å) | | 主引用文献 | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation
Nat.Struct.Mol.Biol., 20, 2013
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4B3Q
 | | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, P51 RT, PRIMER DNA, ... | | 著者 | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | | 登録日 | 2012-07-25 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (5 Å) | | 主引用文献 | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation
Nat.Struct.Mol.Biol., 20, 2013
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4B3O
 | | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | | 分子名称: | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, 5'-D(*CP*GP*TP*AP*TP*GP*CP*CP*TP*AP*TP*AP*GP*TP *TP*AP*TP*TP*GP*TP*GP*GP*CP*C)-3', 5'-R(*AP*UP*GP*AP*3DRP*GP*GP*CP*CP*AP*CP*AP*AP*UP*AP *AP*CP*UP*AP*UP*AP*GP*GP*CP*AP*UP*A)-3', ... | | 著者 | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | | 登録日 | 2012-07-25 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation
Nat.Struct.Mol.Biol., 20, 2013
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7UII
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8VOL
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8VOM
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8VON
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2NV3
 | | Solution structure of L8A mutant of HIV-1 myristoylated matrix protein | | 分子名称: | Gag polyprotein, MYRISTIC ACID | | 著者 | Saad, J.S, Loeliger, E, Luncsford, P, Liriano, M, Tai, J, Kim, A, Miller, J, Joshi, A, Freed, E.O, Summers, M.F. | | 登録日 | 2006-11-10 | | 公開日 | 2007-02-06 | | 最終更新日 | 2024-10-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Point mutations in the HIV-1 matrix protein turn off the myristyl switch.
J.Mol.Biol., 366, 2007
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4M1V
 | | Crystal structure of the ancestral soluble variant of the Human Phosphate Binding Protein (HPBP) | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ... | | 著者 | Gonzalez, D, Hiblot, J, Darbinian, N, Miller, J.S, Gotthard, G, Amini, S, Chabriere, E, Elias, M. | | 登録日 | 2013-08-04 | | 公開日 | 2014-01-01 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Ancestral mutations as a tool for solubilizing proteins: The case of a hydrophobic phosphate-binding protein.
FEBS Open Bio, 4, 2014
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7R6R
 | | Crystal Structure of a Mycobacteriophage Cluster A2 Immunity Repressor:DNA Complex | | 分子名称: | DNA (5'-D(P*CP*CP*CP*GP*CP*TP*TP*GP*AP*CP*AP*GP*CP*CP*AP*CP*CP*GP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*CP*GP*GP*TP*GP*GP*CP*TP*GP*TP*CP*AP*AP*GP*CP*GP*GP*G)-3'), Immunity repressor | | 著者 | McGinnis, R.J, Brambley, C.A, Stamey, B, Green, W.C, Gragg, K.N, Cafferty, E.R, Terwilliger, T.C, Hammel, M, Hollis, T.J, Miller, J.M, Gainey, M.D, Wallen, J.R. | | 登録日 | 2021-06-23 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence.
Nat Commun, 13, 2022
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7RZN
 | | Crystal Structure of Ferritin grown by microbatch method in presence of agarose and electric field 2.1KV | | 分子名称: | CADMIUM ION, Ferritin light chain, SULFATE ION | | 著者 | Aditya, S, Priyadharshine, R, Maham, I, Miller, J.D, Stojanoff, V. | | 登録日 | 2021-08-27 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Crystal Structure of Ferritin grown by microbatch method in presence of agarose and electric field 2.1KV
To Be Published
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7RZX
 | | Crystal Structure of Ferritin grown by microbatch method in presence of agarose and electric field 4.3KV | | 分子名称: | CADMIUM ION, Ferritin light chain, SULFATE ION | | 著者 | Aditya, S, Priyadharshine, R, Maham, I, Miller, J.D, Stojanoff, V. | | 登録日 | 2021-08-27 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Crystal Structure of Ferritin grown by microbatch method in presence of agarose and electric field 4.3KV
To Be Published
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6U5J
 | | CryoEM Structure of Pyocin R2 - postcontracted - collar | | 分子名称: | Collar PA0615, Sheath PA0622 | | 著者 | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | | 登録日 | 2019-08-27 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
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6VE6
 | | A structural characterization of poly(aspartic acid) hydrolase-1 from Sphingomonas sp. KT-1. | | 分子名称: | Poly(Aspartic acid) hydrolase-1 | | 著者 | Bolay, A.L, Salvo, H, Brambley, C.A, Yared, T.J, Miller, J.M, Wallen, J.R, Weiland, M.H. | | 登録日 | 2019-12-28 | | 公開日 | 2020-12-09 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.446 Å) | | 主引用文献 | Structural Characterization of Sphingomonas sp. KT-1 PahZ1-Catalyzed Biodegradation of Thermally Synthesized Poly(aspartic acid)
Acs Sustain Chem Eng, 2020
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6PYT
 | | CryoEM Structure of Pyocin R2 - precontracted - trunk | | 分子名称: | Pyocin sheath PA0622, Pyocin tube PA0623 | | 著者 | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | | 登録日 | 2019-07-30 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
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4OL8
 | | Ty3 reverse transcriptase bound to DNA/RNA | | 分子名称: | 5'-D(*CP*AP*TP*CP*TP*TP*CP*CP*TP*CP*TP*CP*TP*CP*TP*C)-3', 5'-R(*CP*UP*GP*AP*GP*AP*GP*AP*GP*AP*GP*GP*AP*AP*GP*AP*UP*G)-3', Reverse transcriptase/ribonuclease H, ... | | 著者 | Nowak, E, Miller, J.T, Bona, M.K, Studnicka, J, Szczepanowski, R.H, Jurkowski, J, Le Grice, S.F.J, Nowotny, M. | | 登録日 | 2014-01-23 | | 公開日 | 2014-03-05 | | 最終更新日 | 2014-04-16 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry.
Nat.Struct.Mol.Biol., 21, 2014
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4O4H
 | | Tubulin-Laulimalide complex | | 分子名称: | CALCIUM ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Prota, A.E, Bargsten, K, Northcote, P.T, Marsh, M, Altmann, K.H, Miller, J.H, Diaz, J.F, Steinmetz, M.O. | | 登録日 | 2013-12-18 | | 公開日 | 2014-03-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of microtubule stabilization by laulimalide and peloruside a.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4O4J
 | | Tubulin-Peloruside A complex | | 分子名称: | CALCIUM ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Prota, A.E, Bargsten, K, Northcote, P.T, Marsh, M, Altmann, K.H, Miller, J.H, Diaz, J.F, Steinmetz, M.O. | | 登録日 | 2013-12-18 | | 公開日 | 2014-03-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of microtubule stabilization by laulimalide and peloruside A.
Angew.Chem.Int.Ed.Engl., 53, 2014
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4O4L
 | | Tubulin-Peloruside A-Epothilone A complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, EPOTHILONE A, ... | | 著者 | Prota, A.E, Bargsten, K, Northcote, P.T, Marsh, M, Altmann, K.H, Miller, J.H, Diaz, J.F, Steinmetz, M.O. | | 登録日 | 2013-12-18 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of microtubule stabilization by laulimalide and peloruside a.
Angew.Chem.Int.Ed.Engl., 53, 2014
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2V59
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2W9S
 | | Staphylococcus aureus S1:DHFR in complex with trimethoprim | | 分子名称: | DIHYDROFOLATE REDUCTASE TYPE 1 FROM TN4003, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Soutter, H.H, Miller, J.R. | | 登録日 | 2009-01-28 | | 公開日 | 2009-03-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Comparison of Chromosomal and Exogenous Dihydrofolate Reductase from Staphylococcus Aureus in Complex with the Potent Inhibitor Trimethoprim.
Proteins, 76, 2009
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2V58
 | | CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1 | | 分子名称: | 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION | | 著者 | Mochalkin, I, Miller, J.R. | | 登録日 | 2008-10-02 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2V5A
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