7TZ1

Crystal Structure of a Mycobacteriophage Cluster A2 Immunity Repressor:DNA Complex

Summary for 7TZ1

• Entry DOI: 10.2210/pdb7tz1/pdb
• Related: 7R6R
• Descriptor: Immunity repressor, DNA (5'-D(P*TP*TP*TP*CP*GP*GP*TP*GP*GP*CP*TP*GP*TP*CP*AP*AP*GP*CP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*GP*CP*TP*TP*GP*AP*CP*AP*GP*CP*CP*AP*CP*CP*GP*AP*AP*A)-3') (3 entities in total)
• Functional Keywords: immunity repressor, helix-turn-helix motif, dna binding protein, gene regulation, gene regulation-dna complex, gene regulation/dna
• Biological source: Mycobacterium phage TipsytheTRex; More
• Total number of polymer chains: 3
• Total formula weight: 36812.38

Authors

McGinnis, R.J.,Brambley, C.A.,Stamey, B.,Green, W.C.,Gragg, K.N.,Cafferty, E.R.,Terwilliger, T.C.,Hammel, M.,Hollis, T.J.,Miller, J.M.,Gainey, M.D.,Wallen, J.R. (deposition date: 2022-02-15, release date: 2022-07-20, Last modification date: 2022-07-27)

• Primary citation: McGinnis, R.J.,Brambley, C.A.,Stamey, B.,Green, W.C.,Gragg, K.N.,Cafferty, E.R.,Terwilliger, T.C.,Hammel, M.,Hollis, T.J.,Miller, J.M.,Gainey, M.D.,Wallen, J.R.; A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence.; Nat Commun, 13:4105-4105, 2022; PubMed: 35835745; DOI: 10.1038/s41467-022-31678-6

Experimental method

X-RAY DIFFRACTION (2.79 Å)