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PDB: 185 results
7TJQ
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BU of 7tjq by Molmil
SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ...
Authors:Hsieh, C.-L, McLellan, J.S, Rush, S.A.
Deposit date:2022-01-16
Release date:2022-09-14
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
7TL0
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BU of 7tl0 by Molmil
Cryo-EM structure of hMPV preF bound by Fabs MPE8 and SAN32-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
Authors:Rush, S.A, Hsieh, C.-L, McLellan, J.S.
Deposit date:2022-01-17
Release date:2022-09-14
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
7USM
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BU of 7usm by Molmil
Integrin alphaM/beta2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2022-04-25
Release date:2022-08-17
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
7UPD
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BU of 7upd by Molmil
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 2B12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2B12 heavy chain, Fab 2B12 light chain, ...
Authors:Byrne, P.O, McLellan, J.S.
Deposit date:2022-04-14
Release date:2023-03-29
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UPA
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BU of 7upa by Molmil
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1H8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 1H8 heavy chain, Fab 1H8 light chain, ...
Authors:Byrne, P.O, McLellan, J.S.
Deposit date:2022-04-14
Release date:2023-03-29
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UPB
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BU of 7upb by Molmil
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1H1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 1H1 heavy chain, Fab 1H1 light chain, ...
Authors:Byrne, P.O, McLellan, J.S.
Deposit date:2022-04-14
Release date:2023-03-29
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UPK
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BU of 7upk by Molmil
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1A9
Descriptor: Fab 1A9 heavy chain, Fab 1A9 light chain, Fusion glycoprotein F0
Authors:Byrne, P.O, McLellan, J.S.
Deposit date:2022-04-15
Release date:2023-03-29
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UR4
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BU of 7ur4 by Molmil
Cryo-EM Structure of the Neutralizing Antibody MPV467 in Complex with Prefusion Human Metapneumovirus F Glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPV467 Fab Heavy chain, ...
Authors:Rush, S.A, McLellan, J.S.
Deposit date:2022-04-21
Release date:2022-06-08
Last modified:2022-06-29
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structural basis for ultrapotent antibody-mediated neutralization of human metapneumovirus.
Proc.Natl.Acad.Sci.USA, 119, 2022
8U1R
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BU of 8u1r by Molmil
Prefusion-stabilized Langya virus F protein, variant G99C/I109C
Descriptor: Fusion glycoprotein F
Authors:Byrne, P.O, McLellan, J.S.
Deposit date:2023-09-01
Release date:2023-12-27
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Prefusion stabilization of the Hendra and Langya virus F proteins.
J.Virol., 98, 2024
8TMA
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BU of 8tma by Molmil
Antibody N3-1 bound to RBD in the up conformation
Descriptor: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2023-07-29
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8U1G
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BU of 8u1g by Molmil
Prefusion-stabilized SARS-CoV-2 S2 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2023-08-31
Release date:2024-01-24
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge.
Nat Commun, 15, 2024
8TM1
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BU of 8tm1 by Molmil
Antibody N3-1 bound to RBDs in the up and down conformations
Descriptor: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2023-07-27
Release date:2024-01-17
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8TW3
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BU of 8tw3 by Molmil
hMPV fusion protein complexed with single domain antibodies sdHMPV16 and sdHMPV12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein, Single domain antibody sdHMPV12, ...
Authors:Rush, S.A, McLellan, J.S.
Deposit date:2023-08-19
Release date:2024-01-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein.
Mbio, 15, 2024
7USL
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BU of 7usl by Molmil
Integrin alphaM/beta2 ectodomain in complex with adenylate cyclase toxin RTX751 and M1F5 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2022-04-25
Release date:2022-08-17
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
6UOE
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BU of 6uoe by Molmil
3-25 Fab germline-reversion variant bound to an HCMV gB-derived peptide
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-25 Fab heavy chain, 3-25 Fab light chain, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2019-10-14
Release date:2020-07-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.
Plos Pathog., 16, 2020
6VKF
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BU of 6vkf by Molmil
CCHFV GP38 (IbAr10200)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GP38
Authors:Mishra, A.K, McLellan, J.S.
Deposit date:2020-01-20
Release date:2020-02-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.524 Å)
Cite:Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38.
J.Virol., 94, 2020
6WAQ
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BU of 6waq by Molmil
Crystal structure of the SARS-CoV-1 RBD bound by the cross-reactive single-domain antibody SARS VHH-72
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, nanobody SARS VHH-72
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2020-03-25
Release date:2020-04-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
Cell, 181, 2020
6VKM
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BU of 6vkm by Molmil
Crystal Structure of Stabilized GP from Makona Variant of Ebola Virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Virion spike glycoprotein
Authors:Gilman, M.S.A, Rutten, L, Langedijk, J.P.M, McLellan, J.S.
Deposit date:2020-01-21
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers.
Cell Rep, 30, 2020
6WAR
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BU of 6war by Molmil
Crystal structure of the MERS-CoV RBD bound by the neutralizing single-domain antibody MERS VHH-55
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein, nanobody MERS VHH-55
Authors:Wrapp, D, Torres, G.M, McLellan, J.S.
Deposit date:2020-03-25
Release date:2020-04-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
Cell, 181, 2020
6VSB
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BU of 6vsb by Molmil
Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Wrapp, D, Wang, N, Corbett, K.S, Goldsmith, J.A, Hsieh, C, Abiona, O, Graham, B.S, McLellan, J.S.
Deposit date:2020-02-10
Release date:2020-02-26
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Science, 367, 2020
8TCO
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BU of 8tco by Molmil
HCMV Trimer in complex with CS2it1p2_F7K Fab and CS4tt1p1_E3K Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CS2it1p2_F7K Fab heavy chain, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2023-07-02
Release date:2023-08-09
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
Immunity, 56, 2023
8TEA
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BU of 8tea by Molmil
HCMV Pentamer in complex with CS2pt1p2_A10L Fab and CS3pt1p4_C1L Fab
Descriptor: CS2pt1p2_A10L Fab heavy chain, CS2pt1p2_A10L Fab light chain, CS3pt1p4_C1L Fab heavy chain, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2023-07-05
Release date:2023-08-09
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer.
Immunity, 56, 2023
6BLI
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BU of 6bli by Molmil
RSV G peptide bound to Fab CB002.5
Descriptor: CB002.5 Fab Heavy Chain, CB002.5 Fab Light Chain, Major surface glycoprotein G
Authors:Jones, H.G, McLellan, J.S, Langedijk, J.P.
Deposit date:2017-11-10
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
6BLH
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BU of 6blh by Molmil
RSV G central conserved region bound to Fab CB017.5
Descriptor: 1,2-ETHANEDIOL, Fab CB017.5 heavy chain, Fab CB017.5 light chain, ...
Authors:Jones, H.G, McLellan, J.S, Langedijk, J.P.
Deposit date:2017-11-10
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
5TP3
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BU of 5tp3 by Molmil
Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4
Descriptor: F-VHH-4
Authors:Wrapp, D, Gilman, M.S.A, McLellan, J.S.
Deposit date:2016-10-19
Release date:2017-02-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.874 Å)
Cite:Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017

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