8TM1

Antibody N3-1 bound to RBDs in the up and down conformations

Replaces:  7SIX

Summary for 8TM1

• Entry DOI: 10.2210/pdb8tm1/pdb
• EMDB information: 41374
• Descriptor: Spike glycoprotein, N3-1 Fab heavy chain, N3-1 Fab light chain (3 entities in total)
• Functional Keywords: sars-cov-2 spike, neutralizing antibody, rbd-directed antibody, quaternary epitope, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 4
• Total formula weight: 311138.92

Authors

Hsieh, C.-L.,McLellan, J.S. (deposition date: 2023-07-27, release date: 2024-01-17)

• Primary citation: Goike, J.,Hsieh, C.L.,Horton, A.P.,Gardner, E.C.,Zhou, L.,Bartzoka, F.,Wang, N.,Javanmardi, K.,Herbert, A.,Abbassi, S.,Xie, X.,Xia, H.,Shi, P.Y.,Renberg, R.,Segall-Shapiro, T.H.,Terrace, C.I.,Wu, W.,Shroff, R.,Byrom, M.,Ellington, A.D.,Marcotte, E.M.,Musser, J.M.,Kuchipudi, S.V.,Kapur, V.,Georgiou, G.,Weaver, S.C.,Dye, J.M.,Boutz, D.R.,McLellan, J.S.,Gollihar, J.D.; SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.; Commun Biol, 6:1250-1250, 2023; PubMed: 38082099; DOI: 10.1038/s42003-023-05649-6

Experimental method

ELECTRON MICROSCOPY (2.79 Å)