5LIO
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6RXO
| Crystal structure of CobB Ac2 (A76G, I131C, V162A) in complex with H4K16-Buturyl peptide | 分子名称: | Histone H4, NAD-dependent protein deacylase, ZINC ION | 著者 | Spinck, M, Gasper, R, Neumann, H. | 登録日 | 2019-06-08 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Evolved, Selective Erasers of Distinct Lysine Acylations. Angew.Chem.Int.Ed.Engl., 59, 2020
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8GT2
| Crystal structure of human cardiac alpha actin P109A mutant (AMPPNP state) in complex with fragmin F1 domain | 分子名称: | 1,2-ETHANEDIOL, Actin, alpha cardiac muscle 1, ... | 著者 | Iwasa, M, Oda, T, Takeda, S. | 登録日 | 2022-09-07 | 公開日 | 2023-03-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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5LJT
| Crystal structure of human carbonic anhydrase II in complex with the 4-((1-phenyl-1H-1,2,3-triazol-4-yl)methoxy)benzenesulfonamide inhibitor | 分子名称: | 4-[[4-[azanyl-bis(oxidanyl)-$l^{4}-sulfanyl]phenoxy]methyl]-1-phenyl-1,2,3-triazole, Carbonic anhydrase 2, GLYCEROL, ... | 著者 | Ferraroni, M, Supuran, C. | 登録日 | 2016-07-19 | 公開日 | 2017-06-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations. J. Med. Chem., 59, 2016
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7CIJ
| Crystal structure of L-methionine decarboxylase from Streptomyces sp.590 in complexed with 3-methlythiopropylamine (external aldimine form). | 分子名称: | L-methionine decarboxylase, [6-methyl-4-[(E)-3-methylsulfanylpropyliminomethyl]-5-oxidanyl-pyridin-3-yl]methyl dihydrogen phosphate | 著者 | Okawa, A, Shiba, T, Hayashi, M, Onoue, Y, Murota, M, Sato, D, Inagaki, J, Tamura, T, Harada, S, Inagaki, K. | 登録日 | 2020-07-07 | 公開日 | 2021-01-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Structural basis for substrate specificity of l-methionine decarboxylase. Protein Sci., 30, 2021
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8GT5
| Crystal structure of human cardiac alpha actin Q137A mutant (ADP-Pi state) in complex with fragmin F1 domain | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | 著者 | Iwasa, M, Oda, T, Takeda, S. | 登録日 | 2022-09-07 | 公開日 | 2023-03-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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8G87
| Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region) | 分子名称: | POU domain, class 5, transcription factor 1, ... | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | 登録日 | 2023-02-17 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
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7R1O
| p62-ZZ domain of the human sequestosome in complex with dusquetide | 分子名称: | Dusquetide, Sequestosome-1, ZINC ION | 著者 | Hakansson, M, Hansson, M, Logan, D.T, Rozek, A, Donini, O. | 登録日 | 2022-02-03 | 公開日 | 2022-05-18 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Dusquetide modulates innate immune response through binding to p62. Structure, 30, 2022
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8G86
| Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of nucleosome) | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | 登録日 | 2023-02-17 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
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8GT3
| Crystal structure of human cardiac alpha actin P109A mutant (ADP-Pi state) in complex with fragmin F1 domain | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | 著者 | Iwasa, M, Oda, T, Takeda, S. | 登録日 | 2022-09-07 | 公開日 | 2023-03-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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7CMM
| Crystal structure of TEAD1-YBD in complex with K-975 | 分子名称: | N-[3-(4-chloranylphenoxy)-4-methyl-phenyl]propanamide, Transcriptional enhancer factor TEF-1 | 著者 | Tsuji, Y, Suzuki, M, Yasunaga, M, Hamguchi, K, Saito, J. | 登録日 | 2020-07-28 | 公開日 | 2021-02-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | The novel potent TEAD inhibitor, K-975, inhibits YAP1/TAZ-TEAD protein-protein interactions and exerts an anti-tumor effect on malignant pleural mesothelioma. Am J Cancer Res, 10, 2020
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8G88
| Human Oct4 bound to nucleosome with human nMatn1 sequence | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | 登録日 | 2023-02-17 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
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8G8B
| Nucleosome with human nMatn1 sequence in complex with Human Oct4 | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | 登録日 | 2023-02-17 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
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2V5Q
| CRYSTAL STRUCTURE OF WILD-TYPE PLK-1 KINASE DOMAIN IN COMPLEX WITH A SELECTIVE DARPIN | 分子名称: | DESIGN ANKYRIN REPEAT PROTEIN, SERINE/THREONINE-PROTEIN KINASE PLK1 | 著者 | Bandeiras, T.M, Hillig, R.C, Matias, P.M, Eberspaecher, U, Fanghaenel, J, Thomaz, M, Miranda, S, Crusius, K, Puetter, V, Amstutz, P, Gulotti-Georgieva, M, Binz, H.K, Holz, C, Schmitz, A.A.P, Lang, C, Donner, P, Egner, U, Carrondo, M.A, Mueller-Tiemann, B. | 登録日 | 2007-07-08 | 公開日 | 2008-04-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin. Acta Crystallogr. D Biol. Crystallogr., 64, 2008
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5FGG
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8GJM
| 17b10 fab in complex with full-length SARS-CoV-2 Spike G614 trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kwon, H.J, Zhang, J, Kosikova, M, Tang, W.C, Rodriguez, U.O, Peng, H.Q, Meseda, C.A, Pedro, C.L, Schmeisser, F, Lu, J.M, Zhou, B, Davis, C.T, Wentworth, D.E, Chen, W.H, Shriver, M.C, Pasetti, M.F, Weir, J.P, Chen, B, Xie, H. | 登録日 | 2023-03-16 | 公開日 | 2023-04-05 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2. J Med Virol, 95, 2023
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8G8E
| Human Oct4 bound to nucleosome with human LIN28B sequence | 分子名称: | LIN28B DNA (32-MER), POU domain, class 5, ... | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | 登録日 | 2023-02-17 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
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5LOU
| human NUDT22 | 分子名称: | Nucleoside diphosphate-linked moiety X motif 22, PHOSPHATE ION | 著者 | Carter, M, Stenmark, P. | 登録日 | 2016-08-10 | 公開日 | 2017-09-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Human NUDT22 Is a UDP-Glucose/Galactose Hydrolase Exhibiting a Unique Structural Fold. Structure, 26, 2018
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2VBU
| Riboflavin kinase Mj0056 from Methanocaldococcus jannaschii in complex with CDP | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Hartmann, M.D, Ammelburg, M, Djuranovic, S, Martin, J, Lupas, A.N, Zeth, K. | 登録日 | 2007-09-16 | 公開日 | 2007-11-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A Ctp-Dependent Archaeal Riboflavin Kinase Forms a Bridge in the Evolution of Cradle-Loop Barrels. Structure, 15, 2007
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5LPY
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8G8G
| Interaction of H3 tail in LIN28B nucleosome with Oct4 | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | 登録日 | 2023-02-17 | 公開日 | 2023-03-22 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
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8G9Z
| High-resolution crystal structure of the human selenomethionine-derived SepSecS-tRNASec complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, ... | 著者 | Puppala, A, Simonovic, M, Castillo Suchkou, J. | 登録日 | 2023-02-22 | 公開日 | 2023-04-05 | 最終更新日 | 2023-05-17 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans. Nucleic Acids Res., 51, 2023
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8GAI
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6RVR
| Atomic structure of the Epstein-Barr portal, structure I | 分子名称: | Portal protein | 著者 | Machon, C, Fabrega-Ferrer, M, Zhou, D, Cuervo, A, Carrascosa, J.L, Stuart, D.I, Coll, M. | 登録日 | 2019-05-31 | 公開日 | 2019-09-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Atomic structure of the Epstein-Barr virus portal. Nat Commun, 10, 2019
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1W19
| Lumazine Synthase from Mycobacterium tuberculosis bound to 3-(1,3,7- trihydro-9-D-ribityl-2,6,8-purinetrione-7-yl)propane 1-phosphate | 分子名称: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, (4S,5S)-1,2-DITHIANE-4,5-DIOL, ... | 著者 | Morgunova, E, Meining, W, Illarionov, B, Haase, I, Fischer, M, Cushman, M, Bacher, A, Ladenstein, R. | 登録日 | 2004-06-03 | 公開日 | 2005-03-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Lumazine Synthase from Mycobacterium Tuberculosis as a Target for Rational Drug Design: Binding Mode of a New Class of Purinetrione Inhibitors(,) Biochemistry, 44, 2005
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