8G87

Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region)

Summary for 8G87

• Entry DOI: 10.2210/pdb8g87/pdb
• Related: 8G86 8G88 8G8B 8G8E 8G8G
• EMDB information: 29837 29841 29843 29845 29846 29850
• Descriptor: nMatn1 DNA (top strand), nMatn1 DNA (bottom strand), POU domain, class 5, transcription factor 1 (3 entities in total)
• Functional Keywords: oct4, nucleosome, pioneer factor, nmatn1 dna, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 157122.90

Authors

Sinha, K.K.,Bilokapic, S.,Du, Y.,Malik, D.,Halic, M. (deposition date: 2023-02-17, release date: 2023-03-22, Last modification date: 2023-07-26)

• Primary citation: Sinha, K.K.,Bilokapic, S.,Du, Y.,Malik, D.,Halic, M.; Histone modifications regulate pioneer transcription factor cooperativity.; Nature, 619:378-384, 2023; PubMed: 37225990; DOI: 10.1038/s41586-023-06112-6

Experimental method

ELECTRON MICROSCOPY (8.1 Å)