8G87

Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region)

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0000122	biological_process	negative regulation of transcription by RNA polymerase II
X	0000976	molecular_function	transcription cis-regulatory region binding
X	0000978	molecular_function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
X	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
X	0001227	molecular_function	DNA-binding transcription repressor activity, RNA polymerase II-specific
X	0001714	biological_process	endodermal cell fate specification
X	0001824	biological_process	blastocyst development
X	0003677	molecular_function	DNA binding
X	0003700	molecular_function	DNA-binding transcription factor activity
X	0003723	molecular_function	RNA binding
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0005739	cellular_component	mitochondrion
X	0005829	cellular_component	cytosol
X	0006355	biological_process	regulation of DNA-templated transcription
X	0006357	biological_process	regulation of transcription by RNA polymerase II
X	0009611	biological_process	response to wounding
X	0009653	biological_process	anatomical structure morphogenesis
X	0009786	biological_process	regulation of asymmetric cell division
X	0010468	biological_process	regulation of gene expression
X	0031625	molecular_function	ubiquitin protein ligase binding
X	0035019	biological_process	somatic stem cell population maintenance
X	0035198	molecular_function	miRNA binding
X	0043565	molecular_function	sequence-specific DNA binding
X	0045944	biological_process	positive regulation of transcription by RNA polymerase II
X	1902894	biological_process	negative regulation of miRNA transcription
X	1990837	molecular_function	sequence-specific double-stranded DNA binding

Functional Information from PROSITE/UniProt

site_id	PS00027
Number of Residues	24
Details	HOMEOBOX_1 'Homeobox' domain signature. IAqqLgLEkdVVRVWFcNrrqkgK

Chain	Residue	Details
X	ILE263-LYS286

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site_id	PS00035
Number of Residues	13
Details	POU_1 POU-specific (POUs) domain signature 1. KRItLGYtQaDVG

Chain	Residue	Details
X	LYS156-GLY168

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site_id	PS00465
Number of Residues	14
Details	POU_2 POU-specific (POUs) domain signature 2. SQTTICRFEaLqLS

Chain	Residue	Details
X	SER180-SER193

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	Region: {"description":"DNA-binding","evidences":[{"source":"UniProtKB","id":"P20263","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P20263","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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