8G9Z
High-resolution crystal structure of the human selenomethionine-derived SepSecS-tRNASec complex
Summary for 8G9Z
| Entry DOI | 10.2210/pdb8g9z/pdb |
| Related | 3HL2 7l1T 7MDL |
| Descriptor | O-phosphoseryl-tRNA(Sec) selenium transferase, RNA (90-MER), (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ... (5 entities in total) |
| Functional Keywords | selenocysteine synthesis, trna-binding, protein biosynthesis, transferase, transferase-rna complex, transferase/rna |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 5 |
| Total formula weight | 265280.33 |
| Authors | Puppala, A.,Simonovic, M.,Castillo Suchkou, J. (deposition date: 2023-02-22, release date: 2023-04-05, Last modification date: 2023-05-17) |
| Primary citation | Puppala, A.K.,Castillo Suchkou, J.,French, R.L.,Kiernan, K.A.,Simonovic, M. Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans. Nucleic Acids Res., 51:4012-4026, 2023 Cited by PubMed: 36929010DOI: 10.1093/nar/gkad182 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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