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7CMM
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BU of 7cmm by Molmil
Crystal structure of TEAD1-YBD in complex with K-975
Descriptor: N-[3-(4-chloranylphenoxy)-4-methyl-phenyl]propanamide, Transcriptional enhancer factor TEF-1
Authors:Tsuji, Y, Suzuki, M, Yasunaga, M, Hamguchi, K, Saito, J.
Deposit date:2020-07-28
Release date:2021-02-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The novel potent TEAD inhibitor, K-975, inhibits YAP1/TAZ-TEAD protein-protein interactions and exerts an anti-tumor effect on malignant pleural mesothelioma.
Am J Cancer Res, 10, 2020

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