6HLW
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6N4Y
| Metabotropic Glutamate Receptor 5 Extracellular Domain with Nb43 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5, ... | 著者 | Koehl, A, Hu, H, Feng, D, Sun, B, Chu, M, Weis, W.I, Mathiesen, J.M, Skiniotis, G, Kobilka, B.K. | 登録日 | 2018-11-20 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.262 Å) | 主引用文献 | Structural insights into the activation of metabotropic glutamate receptors. Nature, 566, 2019
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6VYI
| Cryo-EM structure of human diacylglycerol O-acyltransferase 1 | 分子名称: | Diacylglycerol O-acyltransferase 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | 著者 | Sui, X, Wang, K, Gluchowski, N, Liao, M, Walther, C.T, Farese, V.R. | 登録日 | 2020-02-26 | 公開日 | 2020-05-13 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme. Nature, 581, 2020
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6FN3
| X-ray structure of animal-like Cryptochrome from Chlamydomonas reinhardtii | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cryptochrome photoreceptor, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Franz, S, Ignatz, E, Wenzel, S, Zielosko, H, Yamamoto, J, Mittag, M, Essen, L.-O. | 登録日 | 2018-02-02 | 公開日 | 2018-08-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii. Nucleic Acids Res., 46, 2018
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6VYT
| Escherichia coli transcription-translation complex A2 (TTC-A2) containing a 15 nt long mRNA spacer, NusG, and fMet-tRNAs at P-site and E-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H, Su, M. | 登録日 | 2020-02-27 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (14 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
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1YMN
| The study of reductive unfolding pathways of RNase A (Y92L mutant) | 分子名称: | Ribonuclease pancreatic | 著者 | Xu, G, Narayan, M, Kurinov, I, Ripoll, D.R, Welker, E, Khalili, M, Ealick, S.E, Scheraga, H.A. | 登録日 | 2005-01-21 | 公開日 | 2006-01-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | A localized specific interaction alters the unfolding pathways of structural homologues. J.Am.Chem.Soc., 128, 2006
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4PFI
| Crystal structure of a tRAP periplasmic solute binding protein from marinobacter aquaeolei VT8 (Maqu_2829, TARGET EFI-510133), apo open structure | 分子名称: | SODIUM ION, TRAP dicarboxylate transporter-DctP subunit | 著者 | Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2014-04-29 | 公開日 | 2014-05-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3024 Å) | 主引用文献 | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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7P5W
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1R52
| Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae | 分子名称: | Chorismate synthase | 著者 | Quevillon-Cheruel, S, Leulliot, N, Meyer, P, Graille, M, Bremang, M, Blondeau, K, Sorel, I, Poupon, A, Janin, J, van Tilbeurgh, H. | 登録日 | 2003-10-09 | 公開日 | 2003-12-23 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae J.Biol.Chem., 279, 2004
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6VZW
| TTLL6 bound to the initiation analog | 分子名称: | (2~{S})-2-[[[(3~{R})-3-acetamido-4-(ethylamino)-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Mahalingan, K.K, Keenen, E.K, Strickland, M, Li, Y, Liu, Y, Ball, H.L, Tanner, T.E, Tjandra, N, Roll-Mecak, A. | 登録日 | 2020-02-28 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes. Nat.Struct.Mol.Biol., 27, 2020
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1JFH
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6T3T
| Structure of the 4-hydroxy-tetrahydrodipicolinate synthase from the thermoacidophilic methanotroph Methylacidiphilum fumariolicum SolV | 分子名称: | 4-hydroxy-tetrahydrodipicolinate synthase, SULFATE ION | 著者 | Schmitz, R, Dietl, A, Mueller, M, Berben, T, Op den Camp, H, Barends, T. | 登録日 | 2019-10-11 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the 4-hydroxy-tetrahydrodipicolinate synthase from the thermoacidophilic methanotroph Methylacidiphilum fumariolicum SolV and the phylogeny of the aminotransferase pathway. Acta Crystallogr.,Sect.F, 76, 2020
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7P6K
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6MZU
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6VJ4
| 1.70 Angstrom Resolution Crystal Structure of Peptidylprolyl Isomerase (PrsA) from Bacillus anthracis | 分子名称: | Peptidylprolyl isomerase PrsA | 著者 | Minasov, G, Shuvalova, L, Kiryukhina, O, Wiersum, G, Endres, M, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-01-14 | 公開日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | 1.70 Angstrom Resolution Crystal Structure of Peptidylprolyl Isomerase (PrsA) from Bacillus anthracis To Be Published
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7TQL
| CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B. | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D. | 登録日 | 2022-01-26 | 公開日 | 2022-04-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Nature, 607, 2022
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7U4S
| Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Candida albicans | 分子名称: | GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase | 著者 | Miranda, R.R, Silva, M, Iulek, J. | 登録日 | 2022-02-28 | 公開日 | 2022-04-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Expression, purification, crystallization and structure of Glyceraldehyde-3-Phosphate Dehydrogenase from Candida albicans, main causative agent of candidiasis Chem. Data Coll., 39, 2022
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1AKQ
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7P5Y
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6HSG
| Crystal structure of Schistosoma mansoni HDAC8 H292M mutant complexed with NCC-149 | 分子名称: | DIMETHYLFORMAMIDE, GLYCEROL, Histone deacetylase, ... | 著者 | Shaik, T.B, Marek, M, Romier, C. | 登録日 | 2018-10-01 | 公開日 | 2018-10-31 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.846 Å) | 主引用文献 | Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
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1AKV
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6HW5
| Yeast 20S proteasome in complex with 18 | 分子名称: | (2~{S})-~{N}-[2-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-2-oxidanylidene-ethyl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Huber, E.M, Groll, M. | 登録日 | 2018-10-11 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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6HT6
| Crystal structure of glutathione transferase Omega 2S from Trametes versicolor in complex with 2,4-dihydroxybenzophenone | 分子名称: | Glutathione S-transferase omega 2S, MAGNESIUM ION, [2,4-bis(oxidanyl)phenyl]-phenyl-methanone | 著者 | Schwartz, M, Favier, F, Didierjean, C. | 登録日 | 2018-10-03 | 公開日 | 2018-10-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.671 Å) | 主引用文献 | Molecular recognition of wood polyphenols by phase II detoxification enzymes of the white rot Trametes versicolor. Sci Rep, 8, 2018
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8A7P
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7P5V
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