6VZW
TTLL6 bound to the initiation analog
Summary for 6VZW
Entry DOI | 10.2210/pdb6vzw/pdb |
Descriptor | Tubulin polyglutamylase TTLL6, (2~{S})-2-[[[(3~{R})-3-acetamido-4-(ethylamino)-4-oxidanylidene-butyl]-phosphonooxy-phosphoryl]methyl]pentanedioic acid, GLYCEROL, ... (6 entities in total) |
Functional Keywords | ttll6, initiation, glutamylase, phosphinic acid, ligase |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 4 |
Total formula weight | 219079.92 |
Authors | Mahalingan, K.K.,Keenen, E.K.,Strickland, M.,Li, Y.,Liu, Y.,Ball, H.L.,Tanner, T.E.,Tjandra, N.,Roll-Mecak, A. (deposition date: 2020-02-28, release date: 2020-08-12, Last modification date: 2023-10-11) |
Primary citation | Mahalingan, K.K.,Keith Keenan, E.,Strickland, M.,Li, Y.,Liu, Y.,Ball, H.L.,Tanner, M.E.,Tjandra, N.,Roll-Mecak, A. Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes. Nat.Struct.Mol.Biol., 27:802-813, 2020 Cited by PubMed: 32747782DOI: 10.1038/s41594-020-0462-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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