6N4Y

Metabotropic Glutamate Receptor 5 Extracellular Domain with Nb43

Summary for 6N4Y

Entry DOI	10.2210/pdb6n4y/pdb
Descriptor	Metabotropic glutamate receptor 5, Nanobody 43, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	cell surface receptor nanobody, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	8
Total formula weight	327595.49
Authors	Koehl, A.,Hu, H.,Feng, D.,Sun, B.,Chu, M.,Weis, W.I.,Mathiesen, J.M.,Skiniotis, G.,Kobilka, B.K. (deposition date: 2018-11-20, release date: 2019-01-23, Last modification date: 2023-10-11)
Primary citation	Koehl, A.,Hu, H.,Feng, D.,Sun, B.,Zhang, Y.,Robertson, M.J.,Chu, M.,Kobilka, T.S.,Laermans, T.,Steyaert, J.,Tarrasch, J.,Dutta, S.,Fonseca, R.,Weis, W.I.,Mathiesen, J.M.,Skiniotis, G.,Kobilka, B.K. Structural insights into the activation of metabotropic glutamate receptors. Nature, 566:79-84, 2019 Cited by PubMed: 30675062 DOI: 10.1038/s41586-019-0881-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.262 Å)

Structure validation