2A2Z
 
 | | Crystal Structure of human deoxycytidine kinase in complex with deoxycytidine and uridine diphosphate | | Descriptor: | 2'-DEOXYCYTIDINE, CALCIUM ION, Deoxycytidine kinase, ... | | Authors: | Godsey, M.H, Ort, S, Sabini, E, Konrad, M, Lavie, A. | | Deposit date: | 2005-06-23 | | Release date: | 2006-01-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.02 Å) | | Cite: | Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization.
Biochemistry, 45, 2006
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2A3T
 | | Cu-containing nitrite reductase | | Descriptor: | COPPER (II) ION, Copper-containing nitrite reductase, MAGNESIUM ION | | Authors: | Jacobson, F, Guo, H, Olesen, K, Okvist, M, Neutze, R, Sjolin, L. | | Deposit date: | 2005-06-27 | | Release date: | 2005-08-02 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structures of the oxidized and reduced forms of nitrite reductase from Rhodobacter sphaeroides 2.4.3 at high pH: changes in the interactions of the type 2 copper.
Acta Crystallogr.,Sect.D, 61, 2005
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6LAC
 | | The structural basis of the beta-carbonic anhydrase CafD (C39A mutant) of the filamentous fungus Aspergillus fumigatus | | Descriptor: | Carbonic anhydrase, ZINC ION | | Authors: | Jiin, M.S, Kim, S, Kim, N.J, Hong, S, Kim, S, Sung, J. | | Deposit date: | 2019-11-12 | | Release date: | 2019-11-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | The structural analysis of non-catalytic zinc binding site in the minor beta-carbonic anhydrase CafD
To be published
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2A4X
 | | Crystal Structure Of Mitomycin C-Binding Protein Complexed with Metal-Free Bleomycin A2 | | Descriptor: | BLEOMYCIN A2, Mitomycin-Binding Protein | | Authors: | Danshiitsoodol, N, de Pinho, C.A, Matoba, Y, Kumagai, T, Sugiyama, M. | | Deposit date: | 2005-06-30 | | Release date: | 2006-07-18 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The Mitomycin C (MMC)-binding Protein from MMC-producing Microorganisms Protects from the Lethal Effect of Bleomycin: Crystallographic Analysis to Elucidate the Binding Mode of the Antibiotic to the Protein
J.Mol.Biol., 360, 2006
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2A61
 | | The crystal structure of transcriptional regulator Tm0710 from Thermotoga maritima | | Descriptor: | transcriptional regulator Tm0710 | | Authors: | Lunin, V.V, Evdokimova, E, Kudritska, M, Chang, C, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2005-07-01 | | Release date: | 2005-07-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The crystal structure of transcriptional regulator Tm0710 from Thermotoga maritima
To be Published
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2AD9
 | | Solution structure of Polypyrimidine Tract Binding protein RBD1 complexed with CUCUCU RNA | | Descriptor: | 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 | | Authors: | Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T. | | Deposit date: | 2005-07-20 | | Release date: | 2005-10-04 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of PTB bound to RNA: specific binding and implications for splicing regulation
Science, 309, 2005
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2A56
 | | fluorescent protein asFP595, A143S, on-state, 5min irradiation | | Descriptor: | GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2 | | Authors: | Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S. | | Deposit date: | 2005-06-30 | | Release date: | 2005-08-16 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure and mechanism of the reversible photoswitch of a fluorescent protein
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AEX
 | | The 1.58A Crystal Structure of Human Coproporphyrinogen Oxidase Reveals the Structural Basis of Hereditary Coproporphyria | | Descriptor: | CITRIC ACID, Coproporphyrinogen III oxidase, mitochondrial | | Authors: | Lee, D.S, Flachsova, E, Bodnarova, M, Demeler, B, Martasek, P, Raman, C.S. | | Deposit date: | 2005-07-24 | | Release date: | 2005-08-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structural basis of hereditary coproporphyria.
Proc.Natl.Acad.Sci.USA, 102, 2005
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2A6M
 | | Crystal Structure of the ISHp608 Transposase | | Descriptor: | ISHp608 transposase | | Authors: | Ronning, D.R, Guynet, C, Ton-Hoang, B, Perez, Z.N, Ghirlando, R, Chandler, M, Dyda, F. | | Deposit date: | 2005-07-03 | | Release date: | 2005-10-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Active site sharing and subterminal hairpin recognition in a new class of DNA transposases.
Mol.Cell, 20, 2005
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8YM2
 | | Crystal structure of AIDA-1 PTB domain in complex with SynGAP NPxF motif | | Descriptor: | Ankyrin repeat and sterile alpha motif domain-containing protein 1B, Ras/Rap GTPase-activating protein SynGAP | | Authors: | Wang, X, Wang, Y, Cai, Q, Zhang, M. | | Deposit date: | 2024-03-08 | | Release date: | 2024-05-29 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity.
J.Mol.Biol., 436, 2024
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248D
 | | CRYSTAL STRUCTURES OF AN A-FORM DUPLEX WITH SINGLE-ADENOSINE BULGES AND A CONFORMATIONAL BASIS FOR SITE SPECIFIC RNA SELF-CLEAVAGE | | Descriptor: | DNA/RNA (5'-R(*GP*CP*GP*)-D(*AP*TP*AP*TP*AP*)-R(*CP*GP*C)-3'), ORTHORHOMBIC, SPERMINE | | Authors: | Portmann, S, Grimm, S, Workman, C, Usman, N, Egli, M. | | Deposit date: | 1996-02-02 | | Release date: | 1996-03-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Crystal structures of an A-form duplex with single-adenosine bulges and a conformational basis for site-specific RNA self-cleavage.
Chem.Biol., 3, 1996
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260D
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8YUU
 | | Cryo-EM structure of the histamine-bound H3R-Gi complex | | Descriptor: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | | Deposit date: | 2024-03-27 | | Release date: | 2024-06-05 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
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8YUV
 | | Cryo-EM structure of the immepip-bound H3R-Gi complex | | Descriptor: | 4-(1H-imidazol-5-ylmethyl)piperidine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | | Deposit date: | 2024-03-27 | | Release date: | 2024-06-05 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
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2AAN
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8YGJ
 | | SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 28-nt) | | Descriptor: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (51-MER), ... | | Authors: | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | | Deposit date: | 2024-02-26 | | Release date: | 2024-06-05 | | Last modified: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
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2AAW
 | | Studies on ligand binding and enzyme inhibition of Plasmodium falciparum glutathione S-transferase | | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, L-TREITOL, S-HEXYLGLUTATHIONE, ... | | Authors: | Hiller, N, Fritz-Wolf, K, Deponte, M, Wende, W, Zimmermann, H, Becker, K. | | Deposit date: | 2005-07-14 | | Release date: | 2006-01-10 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Plasmodium falciparum glutathione S-transferase--structural and mechanistic studies on ligand binding and enzyme inhibition.
Protein Sci., 15, 2006
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2ABI
 | | Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone | | Descriptor: | DESOXYCORTICOSTERONE, Mineralocorticoid receptor | | Authors: | Huyet, J, Pinon, G.-M, Rochel, M, Mayer, C, Rafestin-Oblin, M.-E, Fagart, J. | | Deposit date: | 2005-07-15 | | Release date: | 2006-07-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone
To be published
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8YUT
 | | Cryo-EM structure of the amthamine-bound H2R-Gs complex | | Descriptor: | 5-(2-azanylethyl)-4-methyl-1,3-thiazol-2-amine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y. | | Deposit date: | 2024-03-27 | | Release date: | 2024-06-05 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
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8Y5V
 | | GII.4 Sydney PD and 2'-FL | | Descriptor: | 1,2-ETHANEDIOL, GII.4 Sydney PD in complex with 2'-FL (powder), alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Hansman, G, Tame, J.R.H, Kher, G, Pancera, M. | | Deposit date: | 2024-02-01 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | GII.4 Sydney PD and 2'-FL
To Be Published
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8YIF
 | | Crystal structure of GH13_30 alpha-glucosidase CmmB in complex with acarviosin | | Descriptor: | Acarviosin, Alpha-glucosidase | | Authors: | Saburi, W, Tagami, T, Yu, J, Ose, T, Yao, M, Mori, H. | | Deposit date: | 2024-02-29 | | Release date: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Molecular mechanism for the substrate specificity of Arthrobacter globiformis M6 alpha-glucosidase CmmB, belonging to glycoside hydrolase family 13 subfamily 30
Food Biosci, 61, 2024
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28DN
 | | CRYSTAL STRUCTURE ANALYSIS OF AN A(DNA) OCTAMER D(GTACGTAC) | | Descriptor: | DNA (5'-D(*GP*TP*AP*CP*GP*TP*AP*C)-3') | | Authors: | Courseille, C, Dautant, A, Hospital, M, Langlois D'Estaintot, B, Precigoux, G, Molko, D, Teoule, R. | | Deposit date: | 1990-05-03 | | Release date: | 1991-07-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure Analysis of an A(DNA) Octamer d(GTACGTAC)
Acta Crystallogr.,Sect.A, 46, 1990
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2A2A
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2A4C
 | | Crystal structure of mouse cadherin-11 EC1 | | Descriptor: | Cadherin-11 | | Authors: | Patel, S.D, Ciatto, C, Chen, C.P, Bahna, F, Schieren, I, Rajebhosale, M, Jessell, T.M, Honig, B, Price, S.R, Shapiro, L. | | Deposit date: | 2005-06-28 | | Release date: | 2006-04-25 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Type II cadherin ectodomain structures: implications for classical cadherin specificity.
Cell(Cambridge,Mass.), 124, 2006
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2A53
 | | fluorescent protein asFP595, A143S, off-state | | Descriptor: | CHLORIDE ION, GFP-like non-fluorescent chromoprotein FP595 chain 1, GFP-like non-fluorescent chromoprotein FP595 chain 2 | | Authors: | Andresen, M, Wahl, M.C, Stiel, A.C, Graeter, F, Schaefer, L, Trowitzsch, S, Weber, G, Eggeling, C, Grubmueller, H, Hell, S.W, Jakobs, S. | | Deposit date: | 2005-06-30 | | Release date: | 2005-08-16 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure and mechanism of the reversible photoswitch of a fluorescent protein
Proc.Natl.Acad.Sci.Usa, 102, 2005
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