2A2Z
Crystal Structure of human deoxycytidine kinase in complex with deoxycytidine and uridine diphosphate
Summary for 2A2Z
Entry DOI | 10.2210/pdb2a2z/pdb |
Related | 2A30 |
Descriptor | Deoxycytidine kinase, CALCIUM ION, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | nucleoside kinase, uridine diphosphate, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : P27707 |
Total number of polymer chains | 4 |
Total formula weight | 119258.90 |
Authors | Godsey, M.H.,Ort, S.,Sabini, E.,Konrad, M.,Lavie, A. (deposition date: 2005-06-23, release date: 2006-01-17, Last modification date: 2023-08-23) |
Primary citation | Godsey, M.H.,Ort, S.,Sabini, E.,Konrad, M.,Lavie, A. Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization. Biochemistry, 45:452-461, 2006 Cited by PubMed: 16401075DOI: 10.1021/bi0518646 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.02 Å) |
Structure validation
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