2A2Z

Crystal Structure of human deoxycytidine kinase in complex with deoxycytidine and uridine diphosphate

Summary for 2A2Z

• Entry DOI: 10.2210/pdb2a2z/pdb
• Related: 2A30
• Descriptor: Deoxycytidine kinase, CALCIUM ION, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: nucleoside kinase, uridine diphosphate, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : P27707
• Total number of polymer chains: 4
• Total formula weight: 119258.90

Authors

Godsey, M.H.,Ort, S.,Sabini, E.,Konrad, M.,Lavie, A. (deposition date: 2005-06-23, release date: 2006-01-17, Last modification date: 2023-08-23)

• Primary citation: Godsey, M.H.,Ort, S.,Sabini, E.,Konrad, M.,Lavie, A.; Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization.; Biochemistry, 45:452-461, 2006; PubMed: 16401075; DOI: 10.1021/bi0518646

Experimental method

X-RAY DIFFRACTION (3.02 Å)