2A30

Crystal structure of human deoxycytidine kinase in complex with deoxycytidine

Summary for 2A30

• Entry DOI: 10.2210/pdb2a30/pdb
• Related: 2A2Z
• Descriptor: Deoxycytidine kinase, CALCIUM ION, 2'-DEOXYCYTIDINE, ... (4 entities in total)
• Functional Keywords: nucleoside kinase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : P27707
• Total number of polymer chains: 4
• Total formula weight: 117545.04

Authors

Godsey, M.H.,Ort, S.,Sabini, E.,Konrad, M.,Lavie, A. (deposition date: 2005-06-23, release date: 2006-01-17, Last modification date: 2023-08-23)

• Primary citation: Godsey, M.H.,Ort, S.,Sabini, E.,Konrad, M.,Lavie, A.; Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization.; Biochemistry, 45:452-461, 2006; PubMed: 16401075; DOI: 10.1021/bi0518646

Experimental method

X-RAY DIFFRACTION (3.02 Å)