2A30
Crystal structure of human deoxycytidine kinase in complex with deoxycytidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Deoxycytidine kinase | polymer | 248 | 29139.0 | 4 | UniProt (P27707) Pfam (PF01712) | Homo sapiens (human) | dCK |
| 2 | E, H (A, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | F, G, I, J (A, B, C, D) | 2'-DEOXYCYTIDINE | non-polymer | 227.2 | 4 | Chemie (DCZ) | |||
| 4 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 4 - 260 (UniProt: P27707)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
| - | Gln 65 | deletion |
| - | Asp 66 | deletion |
| - | Glu 67 | deletion |
| - | Phe 68 | deletion |
| - | Glu 69 | deletion |
| - | Glu 70 | deletion |
| - | Leu 71 | deletion |
| - | Thr 72 | deletion |
| - | Met 73 | deletion |
| - | Ser 74 | deletion |
| - | Gln 75 | deletion |
| - | Lys 76 | deletion |
| - | Asn 77 | deletion |
| - | Gly 78 | deletion |
| - | Gly 79 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116556.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 989.0 | |
| All* | Total formula weight | 117545.0 |
