1YPV
 
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3OJY
 | | Crystal Structure of Human Complement Component C8 | | 分子名称: | CALCIUM ION, Complement component C8 alpha chain, Complement component C8 beta chain, ... | | 著者 | Lovelace, L.L, Cooper, C.L, Sodetz, J.M, Lebioda, L. | | 登録日 | 2010-08-23 | | 公開日 | 2011-04-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J.Biol.Chem., 286, 2011
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2ONB
 | | Human Thymidylate Synthase at low salt conditions with PDPA bound | | 分子名称: | 1,2-ETHANEDIOL, PROPANE-1,3-DIYLBIS(PHOSPHONIC ACID), SULFATE ION, ... | | 著者 | Lovelace, L.L, Gibson, L.M, Lebioda, L. | | 登録日 | 2007-01-23 | | 公開日 | 2007-04-10 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Cooperative Inhibition of Human Thymidylate Synthase by Mixtures of Active Site Binding and Allosteric Inhibitors
Biochemistry, 46, 2007
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2QOS
 | | Crystal structure of complement protein C8 in complex with a peptide containing the C8 binding site on C8 | | 分子名称: | Complement component 8, gamma polypeptide, Complement component C8 alpha chain | | 著者 | Lovelace, L.L, Chiswell, B, Slade, D.J, Sodetz, J.M, Lebioda, L. | | 登録日 | 2007-07-20 | | 公開日 | 2007-10-16 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: Implications for C8gamma ligand binding.
Mol.Immunol., 45, 2008
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3EGY
 | | Crystal Structure of Human Thymidyalte Synthase A191K with Loop 181-197 stabilized in the inactive conformation | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase | | 著者 | Lovelace, L.L, Gibson, L.M, Johnson, S.R, Berger, S.H, Lebioda, L. | | 登録日 | 2008-09-11 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformation.
Protein Sci., 18, 2009
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3EHI
 | | Crystal Structure of Human Thymidyalte Synthase M190K with Loop 181-197 stabilized in the inactive conformation | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase | | 著者 | Lovelace, L.L, Gibson, L.M, Johnson, S.R, Berger, S.H, Lebioda, L. | | 登録日 | 2008-09-12 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformation.
Protein Sci., 18, 2009
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4H07
 | | Complex of G65T Myoglobin with Phenol in its Proximal Cavity | | 分子名称: | 1,2-ETHANEDIOL, Myoglobin, PHENOL, ... | | 著者 | Lebioda, L, Lovelace, L.L, Celeste, L.R, Huang, X, Wang, C, Shengfang, S, Dawson, J.H. | | 登録日 | 2012-09-07 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | Complex of myoglobin with phenol bound in a proximal cavity.
Acta Crystallogr.,Sect.F, 68, 2012
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2RDA
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2R8U
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2RD8
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2RD7
 | | Human Complement Membrane Attack Proteins Share a Common Fold with Bacterial Cytolysins | | 分子名称: | CHLORIDE ION, Complement component C8 alpha chain, Complement component C8 gamma chain | | 著者 | Slade, D.J, Lovelace, L.L, Chruszcz, M, Minor, W, Lebioda, L, Sodetz, J.M. | | 登録日 | 2007-09-21 | | 公開日 | 2008-05-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
J. Biol. Chem., 286, 2011
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2AKZ
 | | Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLUORIDE ION, Gamma enolase, ... | | 著者 | Qin, J, Chai, G, Brewer, J.M, Lovelace, L.L. | | 登録日 | 2005-08-04 | | 公開日 | 2006-03-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Fluoride inhibition of enolase: crystal structure and thermodynamics
Biochemistry, 45, 2006
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3OB7
 | | Human Thymidylate Synthase R163K with Cys 195 covalently modified by Glutathione | | 分子名称: | GLUTATHIONE, PHOSPHATE ION, Thymidylate synthase | | 著者 | Gibson, L.M, Celeste, L.R, Lovelace, L.L, Lebioda, L. | | 登録日 | 2010-08-06 | | 公開日 | 2010-12-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structures of human thymidylate synthase R163K with dUMP, FdUMP and glutathione show asymmetric ligand binding.
Acta Crystallogr.,Sect.D, 67, 2011
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2AKM
 | | Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Gamma enolase, MAGNESIUM ION, ... | | 著者 | Qin, J, Chai, G, Brewer, J.M, Lovelace, L.L. | | 登録日 | 2005-08-03 | | 公開日 | 2006-03-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Fluoride inhibition of enolase: crystal structure and thermodynamics
Biochemistry, 45, 2006
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2EVP
 | | The Structures of Thiolate- and Carboxylate-Ligated Ferric H93G Myoglobin: Models for Cytochrome P450 and for Oxyanion-Bound Heme Proteins | | 分子名称: | BETA-MERCAPTOETHANOL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Qin, J, Perera, R, Lovelace, L.L, Dawson, J.H, Lebioda, L. | | 登録日 | 2005-10-31 | | 公開日 | 2006-03-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structures of Thiolate- and Carboxylate-Ligated Ferric H93G Myoglobin: Models for Cytochrome P450 and for Oxyanion-Bound Heme Proteins(,).
Biochemistry, 45, 2006
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2EVK
 | | The Structures of Thiolate- and Carboxylate-Ligated Ferric H93G Myoglobin: Models for Cytochrome P450 and for Oxyanion-Bound Heme Proteins | | 分子名称: | ACETIC ACID, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Qin, J, Perera, R, Lovelace, L.L, Dawson, J.H, Lebioda, L. | | 登録日 | 2005-10-31 | | 公開日 | 2006-04-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structures of thiolate- and carboxylate-ligated ferric H93G myoglobin: models for cytochrome P450 and for oxyanion-bound heme proteins.
Biochemistry, 45, 2006
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2OVD
 | | Crystal Structure of Human Complement Protein C8gamma with Laurate | | 分子名称: | Complement component 8, gamma polypeptide, LAURIC ACID | | 著者 | Chiswell, B, Lovelace, L.L, Brannen, C, Ortlund, E.A, Lebioda, L, Sodetz, J.M. | | 登録日 | 2007-02-13 | | 公開日 | 2007-05-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural features of the ligand binding site on human complement protein C8gamma: A member of the lipocalin family
Biochim.Biophys.Acta, 1774, 2007
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2OVE
 | | Crystal Structure of Recombinant Human Complement Protein C8gamma | | 分子名称: | Complement component 8, gamma polypeptide | | 著者 | Chiswell, B, Lovelace, L.L, Brannen, C, Ortlund, E.A, Lebioda, L, Sodetz, J.M. | | 登録日 | 2007-02-13 | | 公開日 | 2007-05-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural features of the ligand binding site on human complement protein C8gamma: A member of the lipocalin family
Biochim.Biophys.Acta, 1774, 2007
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2OVA
 | | X-ray structure of Human Complement Protein C8gamma Y83W Mutant | | 分子名称: | Complement component 8, gamma polypeptide | | 著者 | Chiswell, B, Lovelace, L.L, Brannen, C, Ortlund, E.A, Lebioda, L, Sodetz, J.M. | | 登録日 | 2007-02-13 | | 公開日 | 2007-05-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural features of the ligand binding site on human complement protein C8gamma: A member of the lipocalin family
Biochim.Biophys.Acta, 1774, 2007
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4OF9
 | | Structure of K42N variant of sperm whale myoglobin | | 分子名称: | 1,2-ETHANEDIOL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Lebioda, L, Wang, C, Lovelace, L.L. | | 登録日 | 2014-01-14 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.241 Å) | | 主引用文献 | Structures of K42N and K42Y sperm whale myoglobins point to an inhibitory role of distal water in peroxidase activity.
Acta Crystallogr.,Sect.D, 70, 2014
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4OOD
 | | Structure of K42Y mutant of sperm whale myoglobin | | 分子名称: | 1,2-ETHANEDIOL, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Lebioda, L, Wang, C, Lovelace, L.L. | | 登録日 | 2014-01-31 | | 公開日 | 2014-11-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Structures of K42N and K42Y sperm whale myoglobins point to an inhibitory role of distal water in peroxidase activity.
Acta Crystallogr.,Sect.D, 70, 2014
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3QUS
 | | Crystal Structure of N10-Formyltetrahydrofolate Synthetase with ATPgS | | 分子名称: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, Formate--tetrahydrofolate ligase, MALEIC ACID, ... | | 著者 | Celeste, L.R, Chai, G, Bielak, M, Lovelace, L.L, Lebioda, L. | | 登録日 | 2011-02-24 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Crystal Strucutre of N10-Formyltetrahydrofolate Synthetase with ATPgS
To be Published
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4JIM
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4JJK
 | | Crystal Structure of N10-Formyltetrahydrofolate Synthetase with Folate | | 分子名称: | 1,2-ETHANEDIOL, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, FOLIC ACID, ... | | 著者 | Celeste, L.R, Lovelace, L.L, Lebioda, L. | | 登録日 | 2013-03-08 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Mechanism of N10-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors.
Protein Sci., 21, 2012
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4JJZ
 | | Crystal Structure of N10-Formyltetrahydrofolate Synthetase with ADP and Formylphosphate | | 分子名称: | 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, ADENOSINE-5'-DIPHOSPHATE, Formate--tetrahydrofolate ligase, ... | | 著者 | Celeste, L.R, Lovelace, L.L, Lebioda, L. | | 登録日 | 2013-03-08 | | 公開日 | 2013-03-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mechanism of N10-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors.
Protein Sci., 21, 2012
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