2AKZ

Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex

Summary for 2AKZ

Related1TE6 2AKM
DescriptorGamma enolase, MAGNESIUM ION, PHOSPHATE ION, ... (6 entities in total)
Functional Keywordsenolase; fluoride inhibition; negative cooperativity; glycolysis; crystal structure; isothermal titration calorimetry, lyase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (By similarity) P09104
Total number of polymer chains2
Total molecular weight96521.45
Authors
Qin, J.,Chai, G.,Brewer, J.M.,Lovelace, L.L. (deposition date: 2005-08-04, release date: 2006-03-21, Last modification date: 2011-07-13)
Primary citation
Qin, J.,Chai, G.,Brewer, J.M.,Lovelace, L.L.,Lebioda, L.
Fluoride inhibition of enolase: crystal structure and thermodynamics
Biochemistry, 45:793-800, 2006
PubMed: 16411755 (PDB entries with the same primary citation)
DOI: 10.1021/bi051558s
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.36 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers40.2%2.5%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2akz
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Molmil generated image of 2akz
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Molmil generated image of 2akz
rotated about y axis by 90°
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