2AKZ

Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Gamma enolase	polymer	439	48018.1	2	UniProt (P09104) Pfam (PF03952) Pfam (PF00113)	Homo sapiens (human)	2-phospho-D-glycerate hydro-lyase; Neural enolase; Neuron-specific enolase; NSE; Enolase 2
2	C, D, I, J (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	E, K (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	F, G, L, M (A, B)	FLUORIDE ION	non-polymer		19.0	4	Chemie (F)
5	H (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
6	N, O (A, B)	water	water		18.0	967	Chemie (HOH)

Sequence modifications

A, B: 1 - 433 (UniProt: P09104)

PDB	External Database	Details
His 434	-	expression tag
His 435	-	expression tag
His 436	-	expression tag
His 437	-	expression tag
His 438	-	expression tag
His 439	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	96036.2
Non-Polymers*	Number of molecules	11
	Total formula weight	485.3
All*	Total formula weight	96521.5

*Water molecules are not included.