2AKZ
Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Gamma enolase | polymer | 439 | 48018.1 | 2 | UniProt (P09104) Pfam (PF03952) Pfam (PF00113) In PDB | Homo sapiens (human) | 2-phospho-D-glycerate hydro-lyase; Neural enolase; Neuron-specific enolase; NSE; Enolase 2 |
2 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
3 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
4 | A, B | FLUORIDE ION | non-polymer | 19.0 | 4 | Chemie (F) | |||
5 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
6 | water | water | 18.0 | 967 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 433 (UniProt: P09104)
PDB | External Database | Details |
---|---|---|
His 434 | - | expression tag |
His 435 | - | expression tag |
His 436 | - | expression tag |
His 437 | - | expression tag |
His 438 | - | expression tag |
His 439 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 96036.2 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 485.3 | |
All* | Total formula weight | 96521.5 |