2AKM

Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex

Summary for 2AKM

• Entry DOI: 10.2210/pdb2akm/pdb
• Related: 1TE6 2AKZ
• Descriptor: Gamma enolase, MAGNESIUM ION, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: enolase; fluoride inhibition; negative cooperativity; glycolysis; crystal structure; isothermal titration calorimetry, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm (By similarity): P09104
• Total number of polymer chains: 2
• Total formula weight: 96421.16

Authors

Qin, J.,Chai, G.,Brewer, J.M.,Lovelace, L.L. (deposition date: 2005-08-03, release date: 2006-03-21, Last modification date: 2023-08-23)

• Primary citation: Qin, J.,Chai, G.,Brewer, J.M.,Lovelace, L.L.,Lebioda, L.; Fluoride inhibition of enolase: crystal structure and thermodynamics; Biochemistry, 45:793-800, 2006; PubMed: 16411755; DOI: 10.1021/bi051558s

Experimental method

X-RAY DIFFRACTION (1.92 Å)