2AKM

Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Gamma enolase	polymer	439	48018.1	2	UniProt (P09104) Pfam (PF03952) Pfam (PF00113) In PDB	Homo sapiens (human)	2-phospho-D-glycerate hydro-lyase; Neural enolase; Neuron-specific enolase; NSE; Enolase 2
2	A, B	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
3	A, B	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	A	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
5		water	water		18.0	377	Chemie (HOH)

Sequence modifications

A, B: 1 - 433 (UniProt: P09104)

PDB	External Database	Details
His 434	-	expression tag
His 435	-	expression tag
His 436	-	expression tag
His 437	-	expression tag
His 438	-	expression tag
His 439	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	96036.2
Non-Polymers*	Number of molecules	6
	Total formula weight	385.0
All*	Total formula weight	96421.2

*Water molecules are not included.