3OJY
Crystal Structure of Human Complement Component C8
Summary for 3OJY
Entry DOI | 10.2210/pdb3ojy/pdb |
Descriptor | Complement component C8 alpha chain, Complement component C8 beta chain, Complement component C8 gamma chain, ... (5 entities in total) |
Functional Keywords | macpf, lipocalin, complement, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P07357 P07358 P07360 |
Total number of polymer chains | 3 |
Total formula weight | 144917.33 |
Authors | Lovelace, L.L.,Cooper, C.L.,Sodetz, J.M.,Lebioda, L. (deposition date: 2010-08-23, release date: 2011-04-13, Last modification date: 2023-09-06) |
Primary citation | Lovelace, L.L.,Cooper, C.L.,Sodetz, J.M.,Lebioda, L. Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement. J.Biol.Chem., 286:17585-17592, 2011 Cited by PubMed: 21454577DOI: 10.1074/jbc.M111.219766 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
Download full validation report