2QOS
Crystal structure of complement protein C8 in complex with a peptide containing the C8 binding site on C8
Summary for 2QOS
Entry DOI | 10.2210/pdb2qos/pdb |
Related | 1IW2 1LF7 2OVA 2OVD 2OVE |
Descriptor | Complement component 8, gamma polypeptide, Complement component C8 alpha chain (3 entities in total) |
Functional Keywords | beta barrel, lipocalin, cleavage on pair of basic residues, complement alternate pathway, complement pathway, cytolysis, egf-like domain, glycoprotein, immune response, innate immunity, membrane attack complex, polymorphism, secreted, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P07357 |
Total number of polymer chains | 2 |
Total formula weight | 20560.16 |
Authors | Lovelace, L.L.,Chiswell, B.,Slade, D.J.,Sodetz, J.M.,Lebioda, L. (deposition date: 2007-07-20, release date: 2007-10-16, Last modification date: 2023-08-30) |
Primary citation | Lovelace, L.L.,Chiswell, B.,Slade, D.J.,Sodetz, J.M.,Lebioda, L. Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: Implications for C8gamma ligand binding. Mol.Immunol., 45:750-756, 2008 Cited by PubMed: 17692377DOI: 10.1016/j.molimm.2007.06.359 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.81 Å) |
Structure validation
Download full validation report