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2QOS

Crystal structure of complement protein C8 in complex with a peptide containing the C8 binding site on C8

Functional Information from GO Data
ChainGOidnamespacecontents
C0002376biological_processimmune system process
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005579cellular_componentmembrane attack complex
C0005886cellular_componentplasma membrane
C0006956biological_processcomplement activation
C0006957biological_processcomplement activation, alternative pathway
C0006958biological_processcomplement activation, classical pathway
C0016020cellular_componentmembrane
C0019841molecular_functionretinol binding
C0031640biological_processkilling of cells of another organism
C0044218cellular_componentother organism cell membrane
C0045087biological_processinnate immune response
C0050778biological_processpositive regulation of immune response
C0070062cellular_componentextracellular exosome
C0072562cellular_componentblood microparticle
C0160257
C1902495cellular_componenttransmembrane transporter complex
Functional Information from PROSITE/UniProt
site_idPS00213
Number of Residues14
DetailsLIPOCALIN Lipocalin signature. NFDaqQFAGTWLLV
ChainResidueDetails
CASN21-VAL34

237423

PDB entries from 2025-06-11

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