8SKU
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![BU of 8sku by Molmil](/molmil-images/mine/8sku) | Structure of human SIgA1 in complex with human CD89 (FcaR1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | 著者 | Liu, Q, Stadtmueller, B.M. | 登録日 | 2023-04-20 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions. Nat Commun, 14, 2023
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8SKV
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6ASY
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![BU of 6asy by Molmil](/molmil-images/mine/6asy) | BiP-ATP2 | 分子名称: | 78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... | 著者 | Liu, Q, Yang, J, Zong, Y, Columbus, L, Zhou, L. | 登録日 | 2017-08-26 | 公開日 | 2017-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s. Nat Commun, 8, 2017
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5XSR
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![BU of 5xsr by Molmil](/molmil-images/mine/5xsr) | novel orally efficacious inhibitors complexed with PARP1 | 分子名称: | 6-fluoranyl-2-(4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-1~{H}-benzimidazole-4-carboxamide, Poly [ADP-ribose] polymerase 1, SULFATE ION | 著者 | Liu, Q, Xu, Y. | 登録日 | 2017-06-15 | 公開日 | 2018-04-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors Eur J Med Chem, 145, 2018
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5XSU
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![BU of 5xsu by Molmil](/molmil-images/mine/5xsu) | novel orally efficacious inhibitors complexed with PARP1 | 分子名称: | 6-fluoranyl-2-(4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-yl)-1~{H}-benzimidazole-4-carboxamide, Poly [ADP-ribose] polymerase 1, SULFATE ION | 著者 | Liu, Q, Xu, Y. | 登録日 | 2017-06-15 | 公開日 | 2018-04-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors Eur J Med Chem, 145, 2018
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5XST
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![BU of 5xst by Molmil](/molmil-images/mine/5xst) | novel orally efficacious inhibitors complexed with PARP1 | 分子名称: | 6-fluoranyl-2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)-1~{H}-benzimidazole-4-carboxamide, Poly [ADP-ribose] polymerase 1, SULFATE ION | 著者 | Liu, Q, Xu, Y. | 登録日 | 2017-06-15 | 公開日 | 2018-04-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors Eur J Med Chem, 145, 2018
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5YA5
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![BU of 5ya5 by Molmil](/molmil-images/mine/5ya5) | CRYSTAL STRUCTURE OF c-MET IN COMPLEX WITH NOVEL INHIBITOR | 分子名称: | 2-[3-(4-methoxybenzyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-1H-indole, Hepatocyte growth factor receptor | 著者 | Liu, Q, Xu, Y. | 登録日 | 2017-08-30 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Discovery, optimization and biological evaluation for novel c-Met kinase inhibitors Eur J Med Chem, 143, 2018
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5Z0S
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7SEV
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![BU of 7sev by Molmil](/molmil-images/mine/7sev) | Crystal structure of E coli contaminant protein YadF co-purified with a plant protein | 分子名称: | Carbonic anhydrase 2, POTASSIUM ION, ZINC ION | 著者 | Chai, L, Zhu, P, Chai, J, Pang, C, Andi, B, McsWeeney, S, Shanklin, J, Liu, Q. | 登録日 | 2021-10-01 | 公開日 | 2021-11-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | AlphaFold Protein Structure Database for Sequence-Independent Molecular Replacement Crystals, 11, 2021
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4U9A
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6D9Z
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![BU of 6d9z by Molmil](/molmil-images/mine/6d9z) | Structure of CysZ, a sulfate permease from Pseudomonas Denitrificans | 分子名称: | Sulfate transporter CysZ, octyl beta-D-glucopyranoside | 著者 | Sanghai, Z.A, Clarke, O.B, Liu, Q, Banerjee, S, Rajashankar, K.R, Hendrickson, W.A, Mancia, F. | 登録日 | 2018-04-30 | 公開日 | 2018-05-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.4021318 Å) | 主引用文献 | Structure-based analysis of CysZ-mediated cellular uptake of sulfate. Elife, 7, 2018
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6D79
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![BU of 6d79 by Molmil](/molmil-images/mine/6d79) | Structure of CysZ, a sulfate permease from Pseudomonas Fragi | 分子名称: | Sulfate transporter CysZ | 著者 | Sanghai, Z.A, Liu, Q, Clarke, O.B, Banerjee, S, Rajashankar, K.R, Hendrickson, W.A, Mancia, F. | 登録日 | 2018-04-24 | 公開日 | 2018-05-16 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (3.501 Å) | 主引用文献 | Structure-based analysis of CysZ-mediated cellular uptake of sulfate. Elife, 7, 2018
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8PFC
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![BU of 8pfc by Molmil](/molmil-images/mine/8pfc) | Crystal structure of binary complex between Aster yellows witches'-broom phytoplasma effector SAP05 and the zinc finger domain of SPL5 from Arabidopsis thaliana | 分子名称: | Sequence-variable mosaic (SVM) signal sequence domain-containing protein, Squamosa promoter-binding-like protein 5, ZINC ION | 著者 | Huang, W, Liu, Q, Maqbool, A, Stevenson, C.E.M, Lawson, D.M, Kamoun, S, Hogenhout, S.A. | 登録日 | 2023-06-15 | 公開日 | 2023-07-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Bimodular architecture of bacterial effector SAP05 that drives ubiquitin-independent targeted protein degradation. Proc.Natl.Acad.Sci.USA, 120, 2023
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8PFD
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![BU of 8pfd by Molmil](/molmil-images/mine/8pfd) | Crystal structure of binary complex between Aster yellows witches'-broom phytoplasma effector SAP05 and the von Willebrand Factor Type A domain of the proteasomal ubiquitin receptor Rpn10 from Arabidopsis thaliana | 分子名称: | 26S proteasome non-ATPase regulatory subunit 4 homolog, Sequence-variable mosaic (SVM) signal sequence domain-containing protein | 著者 | Huang, W, Liu, Q, Maqbool, A, Stevenson, C.E.M, Lawson, D.M, Kamoun, S, Hogenhout, S.A. | 登録日 | 2023-06-15 | 公開日 | 2023-07-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Bimodular architecture of bacterial effector SAP05 that drives ubiquitin-independent targeted protein degradation. Proc.Natl.Acad.Sci.USA, 120, 2023
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4WD8
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1BHL
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![BU of 1bhl by Molmil](/molmil-images/mine/1bhl) | CACODYLATED CATALYTIC DOMAIN OF HIV-1 INTEGRASE | 分子名称: | HIV-1 INTEGRASE | 著者 | Maignan, S, Guilloteau, J.P, Zhou-Liu, Q, Clement-Mella, C, Mikol, V. | 登録日 | 1998-06-10 | 公開日 | 1998-10-14 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases. J.Mol.Biol., 282, 1998
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1BI4
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![BU of 1bi4 by Molmil](/molmil-images/mine/1bi4) | CATALYTIC DOMAIN OF HIV-1 INTEGRASE | 分子名称: | INTEGRASE | 著者 | Maignan, S, Guilloteau, J.P, Zhou-Liu, Q, Clement-Mella, C, Mikol, V. | 登録日 | 1998-06-22 | 公開日 | 1998-11-04 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases. J.Mol.Biol., 282, 1998
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1BL3
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![BU of 1bl3 by Molmil](/molmil-images/mine/1bl3) | CATALYTIC DOMAIN OF HIV-1 INTEGRASE | 分子名称: | INTEGRASE, MAGNESIUM ION | 著者 | Maignan, S, Guilloteau, J.P, Zhou-Liu, Q, Clement-Mella, C, Mikol, V. | 登録日 | 1998-07-23 | 公開日 | 1998-09-30 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases. J.Mol.Biol., 282, 1998
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7YP3
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![BU of 7yp3 by Molmil](/molmil-images/mine/7yp3) | Crystal structure of elaiophylin glycosyltransferase in complex with elaiophylin | 分子名称: | ACETATE ION, Elaiophylin, GLYCEROL, ... | 著者 | Xu, T, Liu, Q, Gan, Q, Liu, J. | 登録日 | 2022-08-02 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation. Acta Crystallogr D Struct Biol, 78, 2022
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7YP6
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![BU of 7yp6 by Molmil](/molmil-images/mine/7yp6) | Crystal structure of elaiophylin glycosyltransferase in complex with UDP | 分子名称: | Glycosyltransferase, R-1,2-PROPANEDIOL, URIDINE-5'-DIPHOSPHATE | 著者 | Xu, T, Liu, Q, Gan, Q, Liu, J. | 登録日 | 2022-08-02 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation. Acta Crystallogr D Struct Biol, 78, 2022
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7YP5
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![BU of 7yp5 by Molmil](/molmil-images/mine/7yp5) | Crystal structure of elaiophylin glycosyltransferase in complex with TDP | 分子名称: | CHLORIDE ION, Glycosyltransferase, R-1,2-PROPANEDIOL, ... | 著者 | Xu, T, Liu, Q, Gan, Q, Liu, J. | 登録日 | 2022-08-02 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation. Acta Crystallogr D Struct Biol, 78, 2022
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7YP4
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![BU of 7yp4 by Molmil](/molmil-images/mine/7yp4) | Crystal structure of elaiophylin glycosyltransferase in apo-form | 分子名称: | Glycosyltransferase, R-1,2-PROPANEDIOL | 著者 | Xu, T, Liu, Q, Gan, Q, Liu, J. | 登録日 | 2022-08-02 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation. Acta Crystallogr D Struct Biol, 78, 2022
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7N1R
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![BU of 7n1r by Molmil](/molmil-images/mine/7n1r) | A novel and unique ATP hydrolysis to AMP by a human Hsp70 BiP | 分子名称: | ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, Endoplasmic reticulum chaperone BiP, ... | 著者 | Yang, J, Musayev, F, Liu, Q. | 登録日 | 2021-05-28 | 公開日 | 2022-01-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | A novel and unique ATP hydrolysis to AMP by a human Hsp70 Binding immunoglobin protein (BiP). Protein Sci., 31, 2022
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1REO
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![BU of 1reo by Molmil](/molmil-images/mine/1reo) | L-amino acid oxidase from Agkistrodon halys pallas | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AHPLAAO, CITRIC ACID, ... | 著者 | Zhang, H, Teng, M, Niu, L, Wang, Y, Wang, Y, Liu, Q, Huang, Q, Hao, Q, Dong, Y, Liu, P. | 登録日 | 2003-11-07 | 公開日 | 2004-05-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Purification, partial characterization, crystallization and structural determination of AHP-LAAO, a novel L-amino-acid oxidase with cell apoptosis-inducing activity from Agkistrodon halys pallas venom. Acta Crystallogr.,Sect.D, 60, 2004
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5GNI
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