4U9A

Sulphur Anomalous Crystal Structure of Asymmetric IRAK4 Dimer

Summary for 4U9A

Entry DOI	10.2210/pdb4u9a/pdb
Related	4U97
Descriptor	Interleukin-1 receptor-associated kinase 4, STAUROSPORINE, SULFATE ION (3 entities in total)
Functional Keywords	kinase, sulphur anomalous, autophosphorylation, transferase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: Q9NWZ3
Total number of polymer chains	2
Total formula weight	70862.19
Authors	Ferrao, R.,Liu, Q.,Wu, H. (deposition date: 2014-08-05, release date: 2014-09-24, Last modification date: 2023-12-27)
Primary citation	Ferrao, R.,Zhou, H.,Shan, Y.,Liu, Q.,Li, Q.,Shaw, D.E.,Li, X.,Wu, H. IRAK4 Dimerization and trans-Autophosphorylation Are Induced by Myddosome Assembly. Mol.Cell, 55:891-903, 2014 Cited by PubMed: 25201411 DOI: 10.1016/j.molcel.2014.08.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation