PDB Search results for query - Protein Data Bank Japan

PDB: 1851 results

FK506 BINDING PROTEIN MUTANT, HOMODIMERIC COMPLEX
Descriptor:	FK506 BINDING PROTEIN
Authors:	Rollins, C.T, Rivera, V.M, Woolfson, D.N, Keenan, T, Hatada, M, Adams, S.E, Andrade, L.J, Yaeger, D, van Schravendijk, M.R, Holt, D.A, Gilman, M, Clackson, T.
Deposit date:	2000-05-07
Release date:	2000-08-09
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	A ligand-reversible dimerization system for controlling protein-protein interactions. Proc.Natl.Acad.Sci.USA, 97, 2000

1AG1

MONOHYDROGEN PHOSPHATE BINDING TO TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE
Descriptor:	PHOSPHATE ION, TRIOSEPHOSPHATE ISOMERASE
Authors:	Verlinde, C.L.M.J, Hol, W.G.J.
Deposit date:	1997-03-28
Release date:	1997-06-16
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (2.36 Å)
Cite:	Anion binding at the active site of trypanosomal triosephosphate isomerase. Monohydrogen phosphate does not mimic sulphate. Eur.J.Biochem., 198, 1991

7NGJ

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	4-methyl-~{N}-(phenylmethyl)piperidine-1-carboxamide, HTH-type transcriptional regulator EthR
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.89 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGD

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	4-methyl-~{N}-(4-phenylbutyl)piperidine-1-carboxamide, HTH-type transcriptional regulator EthR
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.47 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGO

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	HTH-type transcriptional regulator EthR, ~{N}-(furan-2-ylmethyl)-4-methyl-piperidine-1-carboxamide
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (2.37 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGX

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	4-methyl-~{N}-undecyl-pyridine-1-carboxamide, HTH-type transcriptional regulator EthR
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.24 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGK

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-cyclohexyl-4-methyl-piperidine-1-carboxamide
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.89 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGT

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-butyl-4-methyl-piperidine-1-carboxamide
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (2.49 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGU

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-(4-methoxyphenyl)-4-methyl-piperidine-1-carboxamide
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.26 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGN

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-cycloheptyl-4-methyl-piperidine-1-carboxamide
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.55 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGR

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	4-methyl-~{N}-[4-(trifluoromethyl)phenyl]piperidine-1-carboxamide, HTH-type transcriptional regulator EthR
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.92 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGS

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	4-methyl-~{N}-pentyl-piperidine-1-carboxamide, HTH-type transcriptional regulator EthR
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGM

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	4-methyl-~{N}-[(1~{R})-1-phenylethyl]piperidine-1-carboxamide, HTH-type transcriptional regulator EthR
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.76 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGI

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-[2-(2-fluorophenyl)ethyl]-4-methyl-piperidine-1-carboxamide
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGY

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	4-methyl-~{N}-[(~{E})-oct-5-enyl]piperidine-1-carboxamide, HTH-type transcriptional regulator EthR
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.27 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

7NGW

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Descriptor:	HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-(4-hydroxyphenyl)-4-methyl-piperidine-1-carboxamide
Authors:	Tomlinson, C.W.E, Tatum, N.J, Pohl, E.
Deposit date:	2021-02-09
Release date:	2022-02-23
Last modified:	2024-01-31
Method:	X-RAY DIFFRACTION (1.26 Å)
Cite:	Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published

4NKC

Human Aldose Reductase complexed with Schl7764 at 1.12 A
Descriptor:	(2Z)-3-(3'-nitrobiphenyl-3-yl)prop-2-enoic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:	Rechlin, C, Heine, A, Klebe, G.
Deposit date:	2013-11-12
Release date:	2015-03-04
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.12 Å)
Cite:	Keys to open the specificity pocket: Biaryl Inhibitors of the human aldose reductase To be Published

4PR4

Human Aldose Reductase complexed with Schl7802 at 1.06 A
Descriptor:	3-(3'-nitrobiphenyl-3-yl)propanoic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:	Rechlin, C, Heine, A, Klebe, G.
Deposit date:	2014-03-05
Release date:	2015-04-08
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.06 Å)
Cite:	Keys to open the specificity pocket: Biphenylic Inhibitors of the human aldose reductase To be Published

4PUW

Human Aldose Reductase complexed with a ligand with an IDD structure (2-[5-fluoro-2-(prop-2-ynylcarbamoyl)phenoxy]acetic acid) at 1.12 A
Descriptor:	Aldose reductase, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:	Rechlin, C, Heine, A, Klebe, G.
Deposit date:	2014-03-14
Release date:	2015-04-08
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.12 Å)
Cite:	Aldose Reductase: How expensive is the opening of the specificity pocket? IDD ligands under investigation To be Published

4PUU

Human Aldose Reductase complexed with a ligand with an IDD structure (2-(2-carbamoyl-5-fluoro-phenoxy)acetic acid) at 1.14 A
Descriptor:	(2-carbamoyl-5-fluorophenoxy)acetic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:	Rechlin, C, Heine, A, Klebe, G.
Deposit date:	2014-03-14
Release date:	2015-04-08
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.14 Å)
Cite:	Human Aldose Reductase: How expensive is the opening of the specificity pocket? IDD ligands under investigation To be Published

1YTQ

Structure of Native Human Beta B2 Crystallin
Descriptor:	Beta crystallin B2
Authors:	Slingsby, C, Smith, M.A, Bateman, O.A.
Deposit date:	2005-02-10
Release date:	2006-01-31
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Mutation of interfaces in domain-swapped human betaB2-crystallin Protein Sci., 16, 2007

4QBX

Human Aldose Reductase complexed with a ligand with an IDD structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid) at 0.98 A
Descriptor:	Aldose reductase, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:	Rechlin, C, Heine, A, Klebe, G.
Deposit date:	2014-05-09
Release date:	2015-07-22
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (0.98 Å)
Cite:	Aldose Reductase: How expensive is the opening of the specificity pocket? IDD ligands under investigation To be Published

4Q7B

Human Aldose Reductase complexed with a ligand with an IDD structure ([2-(benzylcarbamoyl)-5-fluorophenoxy]acetic acid) at 1.19 A
Descriptor:	Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [2-(benzylcarbamoyl)-5-fluorophenoxy]acetic acid
Authors:	Rechlin, C, Heine, A, Klebe, G.
Deposit date:	2014-04-24
Release date:	2015-06-10
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.19 Å)
Cite:	Aldose Reductase: How expensive is the opening of the specificity pocket? IDD ligands under investigation To be Published

4PRR

Human Aldose Reductase complexed with Schl7815 ((3-[3-(5-NITROFURAN-2-YL)PHENYL]PROPANOIC ACID)at 1.01 A
Descriptor:	3-[3-(5-nitrofuran-2-yl)phenyl]propanoic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:	Rechlin, C, Heine, A, Klebe, G.
Deposit date:	2014-03-06
Release date:	2015-04-08
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.01 Å)
Cite:	Keys to open the specificity pocket: Biphenylic Inhibitors of the human aldose reductase To be Published

4PRT

Human Aldose Reductase complexed with Schl12221 ({2-[5-(3-NITROPHENYL)FURAN-2-YL]PHENYL}ACETIC ACID) at 0.96 A
Descriptor:	Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {2-[5-(3-nitrophenyl)furan-2-yl]phenyl}acetic acid
Authors:	Rechlin, C, Heine, A, Klebe, G.
Deposit date:	2014-03-06
Release date:	2015-04-08
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (0.96 Å)
Cite:	Keys to open the specificity pocket: Biphenylic Inhibitors of the human aldose reductase To be Published

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Total results:	1851
Displayed results:	25
Sorted by:	Hit score (from highest)
Deposition authors:	"Lin, C"