7NGN

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound

Summary for 7NGN

• Entry DOI: 10.2210/pdb7ngn/pdb
• Related: 7NGD 7NGG 7NGI 7NGJ 7NGK 7NGM
• Descriptor: HTH-type transcriptional regulator EthR, ~{N}-cycloheptyl-4-methyl-piperidine-1-carboxamide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: ethr, tuberculosis, inhibition, transcription
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 24116.14

Authors

Tomlinson, C.W.E.,Tatum, N.J.,Pohl, E. (deposition date: 2021-02-09, release date: 2022-02-23, Last modification date: 2024-01-31)

• Primary citation: Tatum, N.J.,Tomlinson, C.W.E.,Frita, R.,Bennett, R.,Baulard, A.R.,Pohl, E.,Kitching, M.O.; Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.55 Å)