7NGR

Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound

Summary for 7NGR

• Entry DOI: 10.2210/pdb7ngr/pdb
• Related: 5NGD 5NGG 5NGI 5NGJ 5NGK 5NGM 5NGN 5NGO
• Descriptor: HTH-type transcriptional regulator EthR, 4-methyl-~{N}-[4-(trifluoromethyl)phenyl]piperidine-1-carboxamide (3 entities in total)
• Functional Keywords: ethr, tuberculosis, inhibition, transcription
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 24068.00

Authors

Tomlinson, C.W.E.,Tatum, N.J.,Pohl, E. (deposition date: 2021-02-09, release date: 2022-02-23, Last modification date: 2024-01-31)

• Primary citation: Tatum, N.J.,Tomlinson, C.W.E.,Frita, R.,Bennett, R.,Baulard, A.R.,Pohl, E.,Kitching, M.O.; Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.92 Å)