7NGT
Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound
Summary for 7NGT
Entry DOI | 10.2210/pdb7ngt/pdb |
Related | 5NGD 5NGG 5NGI 5NGJ 5NGK 5NGM 5NGN 5NGO 5NGR 5NGS |
Descriptor | HTH-type transcriptional regulator EthR, ~{N}-butyl-4-methyl-piperidine-1-carboxamide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | ethr, tuberculosis, inhibition, transcription |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 24076.07 |
Authors | Tomlinson, C.W.E.,Tatum, N.J.,Pohl, E. (deposition date: 2021-02-09, release date: 2022-02-23, Last modification date: 2024-01-31) |
Primary citation | Tatum, N.J.,Tomlinson, C.W.E.,Frita, R.,Bennett, R.,Baulard, A.R.,Pohl, E.,Kitching, M.O. Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)