1VM3
| |
1VM2
| |
1VM4
| |
8T07
| Structure of mouse Myomaker mutant-Y118A bound to Fab18G7 | Descriptor: | 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
|
|
8T03
| Structure of mouse Myomaker bound to Fab18G7 in detergent | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
|
|
8T06
| Structure of mouse Myomaker mutant-R107A bound to Fab18G7 | Descriptor: | 18G7 Fab heavy chain, 18G7 Fab light chain, Protein myomaker, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
|
|
8T04
| Structure of mouse Myomaker bound to Fab18G7 in nanodiscs | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 18G7 Fab heavy chain, 18G7 Fab light chain, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
|
|
8T05
| Structure of Ciona Myomaker bound to Fab1A1 | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1A1 Fab heavy chain, 1A1 Fab light chain, ... | Authors: | Long, T, Li, X. | Deposit date: | 2023-05-31 | Release date: | 2023-09-27 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Cryo-EM structures of Myomaker reveal a molecular basis for myoblast fusion. Nat.Struct.Mol.Biol., 30, 2023
|
|
2OQI
| Human Dipeptidyl Peptidase IV (DPP4) with Piperidinone-constrained phenethylamine | Descriptor: | (4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE, Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) | Authors: | Pei, Z, Li, X, von Geldern, T.W, Longenecker, K.L, Pireh, D, Stewart, K.D, Backes, B.J, Lai, C, Lubben, T.H, Ballaron, S.J, Beno, D.W, Kempf-Grote, A.J, Sham, H.L, Trevillyan, J.M. | Deposit date: | 2007-01-31 | Release date: | 2007-04-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Discovery and Structure-Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors. J.Med.Chem., 50, 2007
|
|
6OYY
| Crystal structure of Mtb aspartate decarboxylase, pyrazinoic acid complex | Descriptor: | Aspartate 1-decarboxylase alpha chain, Aspartate 1-decarboxylase beta chain, PYRAZINE-2-CARBOXYLIC ACID | Authors: | Sun, Q, Li, X, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2019-05-15 | Release date: | 2020-02-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD. Nat Commun, 11, 2020
|
|
6P02
| Crystal structure of Mtb aspartate decarboxylase, 6-Chlorine pyrazinoic acid complex | Descriptor: | 6-chloropyrazine-2-carboxylic acid, Aspartate 1-decarboxylase alpha chain, Aspartate 1-decarboxylase beta chain | Authors: | Sun, Q, Li, X, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2019-05-16 | Release date: | 2020-02-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD. Nat Commun, 11, 2020
|
|
2OQV
| Human Dipeptidyl Peptidase IV (DPP4) with piperidine-constrained phenethylamine | Descriptor: | (3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE, Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV) | Authors: | Pei, Z, Li, X, von Geldern, T.W, Longenecker, K.L, Pireh, D, Stewart, K.D. | Deposit date: | 2007-02-01 | Release date: | 2007-04-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Discovery and Structure-Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors. J.Med.Chem., 50, 2007
|
|
6OZ8
| |
6P1Y
| Crystal structure of Mtb aspartate decarboxylase mutant M117I | Descriptor: | AMMONIUM ION, Aspartate 1-decarboxylase alpha chain, Aspartate 1-decarboxylase beta chain, ... | Authors: | Sun, Q, Li, X, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2019-05-20 | Release date: | 2020-02-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD. Nat Commun, 11, 2020
|
|
6PSL
| Structure of a N-Me-D-Gln4,D-aza-Thr8,Arg10-teixobactin analogue | Descriptor: | CHLORIDE ION, teixobactin analogue | Authors: | Nowick, J.S, Yang, H, Pishenko, A, Li, X. | Deposit date: | 2019-07-12 | Release date: | 2019-11-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Design, Synthesis, and Study of Lactam and Ring-Expanded Analogues of Teixobactin. J.Org.Chem., 85, 2020
|
|
2VVZ
| Structure of the catalytic domain of Streptococcus pneumoniae sialidase NanA | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, CHLORIDE ION, SIALIDASE A | Authors: | Xu, G, Li, X, Andrew, P.W, Taylor, G.L. | Deposit date: | 2008-06-13 | Release date: | 2008-06-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the Catalytic Domain of Streptococcus Pneumoniae Sialidase Nana. Acta Crystallogr.,Sect.F, 64, 2008
|
|
4MY5
| Crystal structure of the aromatic amino acid aminotransferase from Streptococcus mutants | Descriptor: | Putative amino acid aminotransferase | Authors: | Cong, X, Li, X, Ge, J, Feng, Y, Feng, X, Li, S. | Deposit date: | 2013-09-27 | Release date: | 2014-10-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.194 Å) | Cite: | Crystal structure of the aromatic-amino-acid aminotransferase from Streptococcus mutans. Acta Crystallogr.,Sect.F, 75, 2019
|
|
1QSR
| CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND ACETYL-COENZYME A | Descriptor: | ACETYL COENZYME *A, TGCN5 HISTONE ACETYL TRANSFERASE | Authors: | Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R. | Deposit date: | 1999-06-23 | Release date: | 1999-09-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Nature, 401, 1999
|
|
1QST
| CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TGCN5 HISTONE ACETYL TRANSFERASE | Authors: | Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R. | Deposit date: | 1999-06-23 | Release date: | 1999-09-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Nature, 401, 1999
|
|
1QSN
| CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND COENZYME A AND HISTONE H3 PEPTIDE | Descriptor: | COENZYME A, HISTONE H3, TGCN5 HISTONE ACETYL TRANSFERASE | Authors: | Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R. | Deposit date: | 1999-06-22 | Release date: | 1999-09-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Nature, 401, 1999
|
|
1QXK
| Monoacid-Based, Cell Permeable, Selective Inhibitors of Protein Tyrosine Phosphatase 1B | Descriptor: | 2-{4-[2-ACETYLAMINO-3-(4-CARBOXYMETHOXY-3-HYDROXY-PHENYL)-PROPIONYLAMINO]-BUTOXY}-6-HYDROXY-BENZOIC ACID METHYL ESTER, Protein-tyrosine phosphatase, non-receptor type 1 | Authors: | Xin, Z, Liu, G, Abad-Zapatero, C, Pei, Z, Szczepankiewick, B.G, Li, X, Zhang, T, Hutchins, C.W, Hajduk, P.J, Ballaron, S.J, Stashko, M.A, Lubben, T.H, Trevillyan, J.M, Jirousek, M.R. | Deposit date: | 2003-09-08 | Release date: | 2003-10-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Identification of a Monoacid-Based, Cell Permeable, Selective
Inhibitor of Protein Tyrosine Phosphatase 1B BIOORG.MED.CHEM.LETT., 13, 2003
|
|
3EQT
| |
7BW7
| Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin. | Descriptor: | Insulin fusion, Insulin receptor | Authors: | Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. | Deposit date: | 2020-04-13 | Release date: | 2021-04-14 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor To Be Published
|
|
7BW8
| Cryo-EM Structure for the Insulin Binding Region in the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin | Descriptor: | Insulin fusion, Insulin receptor | Authors: | Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. | Deposit date: | 2020-04-14 | Release date: | 2021-04-14 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor To Be Published
|
|
7BWA
| Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 2 Insulin | Descriptor: | Insulin fusion, Insulin receptor | Authors: | Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. | Deposit date: | 2020-04-14 | Release date: | 2021-04-14 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor To Be Published
|
|