3EQT

Crystal structure of human LGP2 C-terminal domain in complex with dsRNA

Summary for 3EQT

• Entry DOI: 10.2210/pdb3eqt/pdb
• Descriptor: ATP-dependent RNA helicase DHX58, 5'-R(*GP*CP*GP*CP*GP*CP*GP*C)-3', ZINC ION, ... (4 entities in total)
• Functional Keywords: innate immunity, rig-i-like helicases, viral rna detection, lgp2-dsrna complex, atp-binding, coiled coil, cytoplasm, helicase, hydrolase, immune response, nucleotide-binding, polymorphism, rna-binding, rna binding protein-rna complex, rna binding protein/rna
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm: Q96C10
• Total number of polymer chains: 4
• Total formula weight: 38682.36

Authors

Li, P.,Li, X. (deposition date: 2008-10-01, release date: 2009-03-10, Last modification date: 2023-09-06)

• Primary citation: Li, X.,Ranjith-Kumar, C.T.,Brooks, M.T.,Dharmaiah, S.,Herr, A.B.,Kao, C.,Li, P.; The RIG-I-like Receptor LGP2 Recognizes the Termini of Double-stranded RNA; J.Biol.Chem., 284:13881-13891, 2009; PubMed: 19278996; DOI: 10.1074/jbc.M900818200

Experimental method

X-RAY DIFFRACTION (2 Å)