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PDB: 439 results

3LCS
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BU of 3lcs by Molmil
Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain
Descriptor: ALK tyrosine kinase receptor, GLYCEROL, STAUROSPORINE
Authors:Lee, C.C.
Deposit date:2010-01-11
Release date:2010-08-04
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Biochem.J., 430, 2010
4ZB1
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BU of 4zb1 by Molmil
Crystal Structure of Blue Chromoprotein sgBP from Stichodactyla Gigantea
Descriptor: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, Blue chromoprotein, sgBP
Authors:Lee, C.C, Ching, C.Y, Tsai, H.J, Wang, A.H.J.
Deposit date:2015-04-14
Release date:2015-08-12
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Chromophore Deprotonation State Alters the Optical Properties of Blue Chromoprotein
Plos One, 10, 2015
2LKP
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BU of 2lkp by Molmil
solution structure of apo-NmtR
Descriptor: HTH-type transcriptional regulator NmtR
Authors:Lee, C, Giedroc, D.
Deposit date:2011-10-18
Release date:2012-04-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution Structure of Mycobacterium tuberculosis NmtR in the Apo State: Insights into Ni(II)-Mediated Allostery.
Biochemistry, 51, 2012
2Z9L
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BU of 2z9l by Molmil
complex structure of SARS-CoV 3C-like protease with JMF1586
Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, diaminozinc
Authors:Lee, C.C, Wang, A.H.
Deposit date:2007-09-20
Release date:2007-12-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007
2Z9J
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Complex structure of SARS-CoV 3C-like protease with EPDTC
Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, zinc(II)hydrogensulfide
Authors:Lee, C.C, Wang, A.H.
Deposit date:2007-09-20
Release date:2007-12-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007
6ABT
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BU of 6abt by Molmil
Crystal structure of transcription factor from Listeria monocytogenes
Descriptor: PadR family transcriptional regulator
Authors:Lee, C, Hong, M.
Deposit date:2018-07-23
Release date:2019-06-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-based molecular characterization and regulatory mechanism of the LftR transcription factor from Listeria monocytogenes: Conformational flexibilities and a ligand-induced regulatory mechanism.
Plos One, 14, 2019
6ABQ
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BU of 6abq by Molmil
Crystal structure of transcription factor from Listeria monocytogenes
Descriptor: CHLORIDE ION, PadR family transcriptional regulator
Authors:Lee, C, Hong, M.
Deposit date:2018-07-23
Release date:2019-06-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based molecular characterization and regulatory mechanism of the LftR transcription factor from Listeria monocytogenes: Conformational flexibilities and a ligand-induced regulatory mechanism.
Plos One, 14, 2019
5VRE
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BU of 5vre by Molmil
Crystal structure of a lysosomal potassium-selective channel TMEM175 homolog from Chamaesiphon Minutus
Descriptor: Putative integral membrane protein
Authors:Lee, C, Guo, J, Jiang, Y.
Deposit date:2017-05-10
Release date:2017-07-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.299 Å)
Cite:The lysosomal potassium channel TMEM175 adopts a novel tetrameric architecture.
Nature, 547, 2017
2Z9K
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BU of 2z9k by Molmil
Complex structure of SARS-CoV 3C-like protease with JMF1600
Descriptor: (dimethylamino)(hydroxy)zinc', 3C-like proteinase, DIMETHYL SULFOXIDE
Authors:Lee, C.C, Wang, A.H.
Deposit date:2007-09-20
Release date:2007-12-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007
2L14
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BU of 2l14 by Molmil
Structure of CBP nuclear coactivator binding domain in complex with p53 TAD
Descriptor: CREB-binding protein, Cellular tumor antigen p53
Authors:Lee, C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2010-07-22
Release date:2010-11-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein.
Biochemistry, 49, 2010
2ETM
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Crystal Structure of Focal Adhesion Kinase Domain Complexed with 7H-Pyrrolo [2,3-d] pyrimidine Derivative
Descriptor: 7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE, Focal adhesion kinase 1
Authors:Lee, C.C.
Deposit date:2005-10-27
Release date:2006-10-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Focal Adhesion Kinase Domain Complexed with ATP and novel 7H-Pyrrolo [2,3-d] pyrimidine scaffolds
To be Published
3TNU
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BU of 3tnu by Molmil
Heterocomplex of coil 2B domains of human intermediate filament proteins, keratin 5 (KRT5) and keratin 14 (KRT14)
Descriptor: Keratin, type I cytoskeletal 14, type II cytoskeletal 5
Authors:Lee, C.H, Kim, M.S, Leahy, D.J, Coulombe, P.A.
Deposit date:2011-09-02
Release date:2012-06-20
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Structural basis for heteromeric assembly and perinuclear organization of keratin filaments.
Nat.Struct.Mol.Biol., 19, 2012
3NOW
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BU of 3now by Molmil
UNC-45 from Drosophila melanogaster
Descriptor: UNC-45 protein, SD10334p
Authors:Lee, C.F, Hauenstein, A.V, Fleming, J.K, Gasper, W.C, Engelke, V, Banumathi, S, Bernstein, S.I, Huxford, T.
Deposit date:2010-06-25
Release date:2011-03-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.992 Å)
Cite:X-ray Crystal Structure of the UCS Domain-Containing UNC-45 Myosin Chaperone from Drosophila melanogaster.
Structure, 19, 2011
2Z9G
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BU of 2z9g by Molmil
Complex structure of SARS-CoV 3C-like protease with PMA
Descriptor: 3C-like proteinase, BENZENE, MERCURY (II) ION
Authors:Lee, C.C, Wang, A.H.
Deposit date:2007-09-19
Release date:2007-12-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
Febs Lett., 581, 2007
5HXN
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BU of 5hxn by Molmil
Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M and E75A mutants) from the Wild Tomato Solanum habrochaites
Descriptor: (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic
Authors:Lee, C.C, Chan, Y.T, Wang, A.H.J.
Deposit date:2016-01-31
Release date:2017-04-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure and Potential Head-to-Middle Condensation Function of aZ,Z-Farnesyl Diphosphate Synthase.
Acs Omega, 2, 2017
5HXO
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BU of 5hxo by Molmil
Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase with D71M, E75A and H103Y Mutants
Descriptor: (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic
Authors:Lee, C.C, Chan, Y.T, Wang, A.H.J.
Deposit date:2016-01-31
Release date:2017-04-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure and Potential Head-to-Middle Condensation Function of aZ,Z-Farnesyl Diphosphate Synthase.
Acs Omega, 2, 2017
5HXT
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BU of 5hxt by Molmil
Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M, E75A and H103Y Mutants) Complexed with IPP and DMSPP
Descriptor: (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ...
Authors:Lee, C.C, Chan, Y.T, Wang, A.H.J.
Deposit date:2016-01-31
Release date:2017-04-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z-Farnesyl Diphosphate Synthase
Acs Omega, 2, 2017
4PX6
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BU of 4px6 by Molmil
SYK catalytic domain in complex with a potent pyridopyrimidinone inhibitor
Descriptor: 7-{[(1R,2S)-2-aminocyclohexyl]amino}-5-(1H-indol-7-ylamino)pyrido[4,3-d]pyrimidin-4(3H)-one, Tyrosine-protein kinase SYK
Authors:Lee, C.C.
Deposit date:2014-03-21
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Syk inhibitors with high potency in presence of blood.
Bioorg.Med.Chem.Lett., 24, 2014
3MKQ
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BU of 3mkq by Molmil
Crystal structure of yeast alpha/betaprime-COP subcomplex of the COPI vesicular coat
Descriptor: Coatomer beta'-subunit, Coatomer subunit alpha
Authors:Lee, C, Goldberg, J.
Deposit date:2010-04-15
Release date:2010-07-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats.
Cell(Cambridge,Mass.), 142, 2010
3MKR
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BU of 3mkr by Molmil
Crystal structure of yeast alpha/epsilon-COP subcomplex of the COPI vesicular coat
Descriptor: Coatomer subunit alpha, Coatomer subunit epsilon
Authors:Lee, C, Goldberg, J.
Deposit date:2010-04-15
Release date:2010-07-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats.
Cell(Cambridge,Mass.), 142, 2010
5CY3
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BU of 5cy3 by Molmil
SYK catalytic domain complexed with a potent and orally bioavailable benzisothiazole inhibitor
Descriptor: (5R)-5-[(1R)-1-{[6-(1-methyl-1H-pyrazol-4-yl)-2,1-benzothiazol-4-yl]oxy}ethyl]-1,3-oxazolidin-2-one, Tyrosine-protein kinase SYK
Authors:Lee, C.C.
Deposit date:2015-07-30
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Orally bioavailable Syk inhibitors with activity in a rat PK/PD model.
Bioorg.Med.Chem.Lett., 25, 2015
2HIW
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BU of 2hiw by Molmil
Crystal Structure of Inactive Conformation Abl Kinase Catalytic Domain Complexed with Type II Inhibitor
Descriptor: 7-AMINO-1-METHYL-3-(2-METHYL-5-{[3-(TRIFLUOROMETHYL)BENZOYL]AMINO}PHENYL)-2-OXO-2,3-DIHYDROPYRIMIDO[4,5-D]PYRIMIDIN-1-IUM, Proto-oncogene tyrosine-protein kinase ABL1
Authors:Lee, C.
Deposit date:2006-06-29
Release date:2006-08-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A general strategy for creating
Chem.Biol., 13, 2006
2Z94
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Complex structure of SARS-CoV 3C-like protease with TDT
Descriptor: 4-methylbenzene-1,2-dithiol, Replicase polyprotein 1ab, ZINC ION
Authors:Lee, C.C, Wang, A.H.
Deposit date:2007-09-17
Release date:2007-12-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors
Febs Lett., 581, 2007
2ZU3
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BU of 2zu3 by Molmil
Complex structure of CVB3 3C protease with TG-0204998
Descriptor: 3C proteinase, N-[(benzyloxy)carbonyl]-3-[(2,2-dimethylpropanoyl)amino]-L-alanyl-N-[(1R)-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}pentyl]-L-leucinamide
Authors:Lee, C.C, Tsui, Y.C, Wang, A.H.-J.
Deposit date:2008-10-12
Release date:2009-01-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009
2ZTX
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BU of 2ztx by Molmil
Complex structure of CVB3 3C protease with EPDTC
Descriptor: 3C proteinase, zinc(II)hydrogensulfide
Authors:Lee, C.C, Wang, A.H.-J.
Deposit date:2008-10-10
Release date:2009-01-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds
J.Biol.Chem., 284, 2009

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