3TNU
Heterocomplex of coil 2B domains of human intermediate filament proteins, keratin 5 (KRT5) and keratin 14 (KRT14)
Summary for 3TNU
| Entry DOI | 10.2210/pdb3tnu/pdb |
| Descriptor | Keratin, type I cytoskeletal 14, Keratin, type II cytoskeletal 5 (3 entities in total) |
| Functional Keywords | coiled-coil, structural support, cytosolic protein |
| Biological source | Homo sapiens (human) More |
| Cellular location | Cytoplasm: P02533 |
| Total number of polymer chains | 2 |
| Total formula weight | 30399.14 |
| Authors | Lee, C.H.,Kim, M.S.,Leahy, D.J.,Coulombe, P.A. (deposition date: 2011-09-02, release date: 2012-06-20, Last modification date: 2012-08-01) |
| Primary citation | Lee, C.H.,Kim, M.S.,Chung, B.M.,Leahy, D.J.,Coulombe, P.A. Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. Nat.Struct.Mol.Biol., 19:707-715, 2012 Cited by PubMed: 22705788DOI: 10.1038/nsmb.2330 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.005 Å) |
Structure validation
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