7WFY
 
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2L95
 | | Solution Structure of Cytotoxic T-Lymphocyte Antigent-2(Ctla protein), Crammer at pH 6.0 | | 分子名称: | Crammer | | 著者 | Tseng, T.S, Cheng, C.S, Liu, Y.N, Lyu, P.C. | | 登録日 | 2011-01-31 | | 公開日 | 2011-12-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin.
Biochem.J., 442, 2012
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2K6S
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2KBV
 | | Structural and functional analysis of TM XI of the NHE1 isoform of thE NA+/H+ exchanger | | 分子名称: | Sodium/hydrogen exchanger 1 | | 著者 | Lee, B.L, Li, X, Liu, Y, Sykes, B.D, Fliegel, L. | | 登録日 | 2008-12-09 | | 公開日 | 2009-01-27 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and Functional Analysis of Transmembrane XI of the NHE1 Isoform of the Na+/H+ Exchanger
J.Biol.Chem., 284, 2009
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4LYP
 | | Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase from Rhizomucor miehei | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Exo-beta-1,4-mannosidase, GUANIDINE | | 著者 | Jiang, Z.Q, Zhou, P, Yang, S.Q, Liu, Y, Yan, Q.J. | | 登録日 | 2013-07-31 | | 公開日 | 2014-08-06 | | 最終更新日 | 2014-11-26 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase.
Acta Crystallogr.,Sect.D, 70, 2014
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4O6P
 | | Structural and functional studies the characterization of C58G/C70G mutant in Cys4 Zinc-finger motif in the recombination mediator protein RecR | | 分子名称: | Recombination protein RecR, ZINC ION | | 著者 | Tang, Q, Liu, Y.P, Yan, X.X, Liang, D.C. | | 登録日 | 2013-12-23 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and functional characterization of Cys4 zinc finger motif in the recombination mediator protein RecR.
DNA Repair (Amst.), 24, 2014
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7CMV
 | | Dopamine Receptor D3R-Gi-PD128907 complex | | 分子名称: | (4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-ol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Xu, P, Huang, S, Mao, C, Krumm, B, Zhou, X, Tan, Y, Huang, X.-P, Liu, Y, Shen, D.-D, Jiang, Y, Yu, X, Jiang, H, Melcher, K, Roth, B, Cheng, X, Zhang, Y, Xu, H. | | 登録日 | 2020-07-29 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-04-07 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structures of the human dopamine D3 receptor-G i complexes.
Mol.Cell, 81, 2021
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7CMU
 | | Dopamine Receptor D3R-Gi-Pramipexole complex | | 分子名称: | (6S)-N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Xu, P, Huang, S, Mao, C, Krumm, B, Zhou, X, Tan, Y, Huang, X.-P, Liu, Y, Shen, D.-D, Jiang, Y, Yu, X, Jiang, H, Melcher, K, Roth, B, Cheng, X, Zhang, Y, Xu, H. | | 登録日 | 2020-07-29 | | 公開日 | 2021-03-10 | | 最終更新日 | 2021-04-07 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structures of the human dopamine D3 receptor-G i complexes.
Mol.Cell, 81, 2021
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7XKW
 | | The 3D strcuture of (-)-cyperene synthase with substrate analogue FSPP | | 分子名称: | (-)-cyperene synthase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE | | 著者 | Yu, S.S, Zhu, P, Liu, Y.B, Ma, S.G, Ye, D, Shao, Y.Z, Li, W.R, Cui, Z.J. | | 登録日 | 2022-04-20 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Characterization and Engineering of Two Highly Paralogous Sesquiterpene Synthases Reveal a Regioselective Reprotonation Switch.
Angew.Chem.Int.Ed.Engl., 63, 2024
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4NRS
 | | Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase (E202A mutant) from Rhizomucor miehei in complex with mannobiose | | 分子名称: | Exo-beta-1,4-mannosidase, beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose | | 著者 | Jiang, Z.Q, Zhou, P, Yang, S.Q, Liu, Y, Yan, Q.J. | | 登録日 | 2013-11-27 | | 公開日 | 2014-11-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase.
Acta Crystallogr.,Sect.D, 70, 2014
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7DQO
 | | Marsupenaeus japonicus ferritin mutant-D132R | | 分子名称: | FE (III) ION, Ferritin | | 著者 | Tan, X, Liu, Y, Zang, J, Zhang, T, Zhao, G. | | 登録日 | 2020-12-24 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | | 主引用文献 | Hyperthermostability of prawn ferritin nanocage facilitates its application as a robust nanovehicle for nutraceuticals.
Int.J.Biol.Macromol., 191, 2021
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4NRR
 | | Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase (E202A mutant) from Rhizomucor miehei in complex with mannosyl-fructose | | 分子名称: | Exo-beta-1,4-mannosidase, beta-D-mannopyranose-(1-4)-beta-D-fructofuranose | | 著者 | Jiang, Z.Q, Zhou, P, Yang, S.Q, Liu, Y, Yan, Q.J. | | 登録日 | 2013-11-27 | | 公開日 | 2014-11-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase.
Acta Crystallogr.,Sect.D, 70, 2014
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1WP8
 | | crystal structure of Hendra Virus fusion core | | 分子名称: | Fusion glycoprotein F0,Fusion glycoprotein F0 | | 著者 | Xu, Y, Liu, Y, Lou, Z, Su, N, Bai, Z, Gao, G.F, Rao, Z. | | 登録日 | 2004-08-31 | | 公開日 | 2005-11-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of Nipah and Hendra virus fusion core proteins
FEBS J., 273, 2006
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6M4P
 | | Cytochrome P450 monooxygenase StvP2 substrate-bound structure | | 分子名称: | 6-methoxy-streptovaricin C, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. | | 登録日 | 2020-03-08 | | 公開日 | 2020-08-12 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis.
Nat Commun, 11, 2020
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6LS4
 | | A novel anti-tumor agent S-40 in complex with tubulin | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(4-cyclopropylphenyl)sulfonylamino]-4-methyl-N-(pyridin-3-ylmethyl)benzamide, GLYCEROL, ... | | 著者 | Du, T, Lin, S, Ji, M, Xue, N, Liu, Y, Zhang, K, Lu, D, Chen, X, Xu, H. | | 登録日 | 2020-01-17 | | 公開日 | 2021-01-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.
Cancer Lett., 495, 2020
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4QP0
 | | Crystal Structure Analysis of the Endo-1,4-beta-mannanase from Rhizomucor miehei | | 分子名称: | Endo-beta-mannanase, SULFATE ION | | 著者 | Zheng, Q.J, Peng, Z, Liu, Y, Yan, Q.J, Chen, Z.Z, Qin, Z. | | 登録日 | 2014-06-22 | | 公開日 | 2014-11-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase.
Acta Crystallogr.,Sect.D, 70, 2014
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4O6O
 | | Structural and functional studies the characterization of Cys4 Zinc-finger motif in the recombination mediator protein RecR | | 分子名称: | IMIDAZOLE, Recombination protein RecR, ZINC ION | | 著者 | Tang, Q, Liu, Y.P, Yan, X.X, Liang, D.C. | | 登録日 | 2013-12-23 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and functional characterization of Cys4 zinc finger motif in the recombination mediator protein RecR.
DNA Repair (Amst.), 24, 2014
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7X8O
 | | NMR Solution Structure of the 2:1 Coptisine-KRAS-G4 Complex | | 分子名称: | 6,7-dihydro[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquino[3,2-a]isoquinolin-5-ium, DNA (24-MER) | | 著者 | Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y. | | 登録日 | 2022-03-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
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7X8N
 | | NMR Solution Structure of the Wild-type Bulge-containing KRAS-G4 | | 分子名称: | DNA (24-mer) | | 著者 | Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y. | | 登録日 | 2022-03-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
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7DQP
 | | Thermal treated Marsupenaeus japonicus ferritin | | 分子名称: | Ferritin | | 著者 | Tan, X, Liu, Y, Zang, J, Zhang, T, Zhao, G. | | 登録日 | 2020-12-24 | | 公開日 | 2021-12-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.203 Å) | | 主引用文献 | Hyperthermostability of prawn ferritin nanocage facilitates its application as a robust nanovehicle for nutraceuticals.
Int.J.Biol.Macromol., 191, 2021
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7DKL
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7EA8
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7EA5
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4LVG
 | | Fragment-based Identification of Amides Derived From trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | | 分子名称: | (1S,2S)-N-[4-(phenylsulfonyl)phenyl]-2-(pyridin-3-yl)cyclopropanecarboxamide, 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, ... | | 著者 | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | | 登録日 | 2013-07-26 | | 公開日 | 2013-09-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg.Med.Chem.Lett., 23, 2013
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7WGW
 | | NMR Solution Structure of a cGMP Fill-in Vacancy G-quadruplex Formed in the Oxidized BLM Gene Promoter | | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, DNA (20-MER) | | 著者 | Wang, K.B, Liu, Y, Li, Y, Li, J, Dickerhoff, J, Yang, M.H, Yang, D, Kong, L.Y. | | 登録日 | 2021-12-29 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter.
J.Am.Chem.Soc., 144, 2022
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