7XKW

The 3D strcuture of (-)-cyperene synthase with substrate analogue FSPP

Summary for 7XKW

Entry DOI	10.2210/pdb7xkw/pdb
EMDB information	33209
Descriptor	(-)-cyperene synthase, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, MAGNESIUM ION (3 entities in total)
Functional Keywords	(-)-cyperene synthase, cyclization mechanism, directed evolution, alphafold2, plant protein
Biological source	Artabotrys hexapetalus
Total number of polymer chains	1
Total formula weight	65712.76
Authors	Yu, S.S.,Zhu, P.,Liu, Y.B.,Ma, S.G.,Ye, D.,Shao, Y.Z.,Li, W.R.,Cui, Z.J. (deposition date: 2022-04-20, release date: 2023-10-25, Last modification date: 2024-04-03)
Primary citation	Ye, D.,Shao, Y.Z.,Li, W.R.,Cui, Z.J.,Gong, T.,Yang, J.L.,Wang, H.Q.,Dai, J.G.,Feng, K.P.,Ma, M.,Ma, S.G.,Liu, Y.B.,Zhu, P.,Yu, S.S. Characterization and Engineering of Two Highly Paralogous Sesquiterpene Synthases Reveal a Regioselective Reprotonation Switch. Angew.Chem.Int.Ed.Engl., 63:e202315674-e202315674, 2024 Cited by PubMed: 38327006 DOI: 10.1002/anie.202315674 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation