7X8N

NMR Solution Structure of the Wild-type Bulge-containing KRAS-G4

Summary for 7X8N

• Entry DOI: 10.2210/pdb7x8n/pdb
• Descriptor: DNA (24-mer) (1 entity in total)
• Functional Keywords: g-quadruplex, kras, dna
• Biological source: Homo sapiens
• Total number of polymer chains: 1
• Total formula weight: 7539.93

Authors

Wang, K.B.,Liu, Y.,Li, J.,Xiao, C.,Gu, W.,Li, Y.,Xia, Y.Z.,Yan, T.,Yang, M.H.,Kong, L.Y. (deposition date: 2022-03-14, release date: 2022-09-07, Last modification date: 2024-05-15)

• Primary citation: Wang, K.B.,Liu, Y.,Li, J.,Xiao, C.,Wang, Y.,Gu, W.,Li, Y.,Xia, Y.Z.,Yan, T.,Yang, M.H.,Kong, L.Y.; Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.; Nat Commun, 13:6016-6016, 2022; PubMed: 36224201; DOI: 10.1038/s41467-022-33761-4

Experimental method

SOLUTION NMR