5ZFW
| Crystal structure of human DUX4 homeodomains bound to A11G DNA mutant | Descriptor: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*GP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*CP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 | Authors: | Li, Y.Y, Wu, B.X, Gan, J.H. | Deposit date: | 2018-03-07 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.103 Å) | Cite: | Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
|
|
5ZFY
| Crystal structure of human DUX4 homeodomains bound to A12C DNA mutant | Descriptor: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*CP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*GP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 | Authors: | Li, Y.Y, Wu, B.X, Gan, J.H. | Deposit date: | 2018-03-07 | Release date: | 2018-10-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
|
|
5Z6Z
| Crystal structure of human DUX4 homeodomains bound to DNA | Descriptor: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4 | Authors: | Li, Y.Y, Wu, B.X, Gan, J.H. | Deposit date: | 2018-01-26 | Release date: | 2018-10-31 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
|
|
8EFN
| Structure of Sp-STING3 from Stylophora pistillata coral in complex with 3',3'-cGAMP | Descriptor: | 1,2-ETHANEDIOL, 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon genes protein | Authors: | Li, Y, Slavik, K.M, Morehouse, B.R, Mears, K, Kranzusch, P.J. | Deposit date: | 2022-09-08 | Release date: | 2023-07-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
|
|
6A6B
| cryo-em structure of alpha-synuclein fiber | Descriptor: | Alpha-synuclein | Authors: | Li, Y.W, Zhao, C.Y, Luo, F, Liu, Z, Gui, X, Luo, Z, Zhang, X, Li, D, Liu, C, Li, X. | Deposit date: | 2018-06-27 | Release date: | 2018-07-11 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Amyloid fibril structure of alpha-synuclein determined by cryo-electron microscopy Cell Res., 28, 2018
|
|
6QPQ
| |
6QNX
| Structure of the SA2/SCC1/CTCF complex | Descriptor: | Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog, Transcriptional repressor CTCF | Authors: | Li, Y, Muir, K.W, Panne, D. | Deposit date: | 2019-02-12 | Release date: | 2020-01-22 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structural basis for cohesin-CTCF-anchored loops. Nature, 578, 2020
|
|
2N7G
| |
2N7R
| |
2N7Q
| |
5Y27
| Crystal structure of Se-Met Dpb4-Dpb3 | Descriptor: | DNA polymerase epsilon subunit D, GLYCEROL, Putative transcription factor C16C4.22 | Authors: | Li, Y, Gao, F, Su, M, Zhang, F.B, Chen, Y.H. | Deposit date: | 2017-07-24 | Release date: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Coordinated regulation of heterochromatin inheritance by Dpb3-Dpb4 complex. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
8GJW
| Structure of a cGAS-like receptor Cv-cGLR1 from C. virginica | Descriptor: | SULFATE ION, cGAS-like receptor 1 | Authors: | Li, Y, Morehouse, B.R, Slavik, K.M, Liu, J, Toyoda, H, Kranzusch, P.J. | Deposit date: | 2023-03-16 | Release date: | 2023-07-05 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
|
|
8GJZ
| Structure of a STING receptor from S. pistillata Sp-STING1 bound to 2'3'-cUA | Descriptor: | 2'3'-cUA, Stimulator of interferon genes protein | Authors: | Li, Y, Toyoda, H, Slavik, K.M, Morehouse, B.R, Kranzusch, P.J. | Deposit date: | 2023-03-16 | Release date: | 2023-07-05 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell, 186, 2023
|
|
8HM0
| F8-A22-E4 complex of MPXV in trimeric form | Descriptor: | DNA polymerase, DNA polymerase processivity factor component A20, E4R | Authors: | Li, Y.N, Shen, Y.P, Hu, Z.W, Yan, R.H. | Deposit date: | 2022-12-02 | Release date: | 2023-05-31 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant. Sci Adv, 9, 2023
|
|
8HLZ
| F8-A22-E4 complex of MPXV in hexameric form | Descriptor: | DNA polymerase, DNA polymerase processivity factor component A20, E4R | Authors: | Li, Y.N, Shen, Y.P, Hu, Z.W, Yan, R.H. | Deposit date: | 2022-12-02 | Release date: | 2023-05-31 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant. Sci Adv, 9, 2023
|
|
8I92
| ACE2-B0AT1 complex bound with glutamine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Li, Y.N, Zhang, Y.Y, Shen, Y.P, Yan, R.H. | Deposit date: | 2023-02-06 | Release date: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B 0 AT1 and ACE2-SIT1. Cell Discov, 9, 2023
|
|
8I91
| ACE2-SIT1 complex bound with proline | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Li, Y.N, Zhang, Y.Y, Shen, Y.P, Yan, R.H. | Deposit date: | 2023-02-06 | Release date: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B 0 AT1 and ACE2-SIT1. Cell Discov, 9, 2023
|
|
8I93
| ACE2-B0AT1 complex bound with methionine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Li, Y.N, Zhang, Y.Y, Shen, Y.P, Yan, R.H. | Deposit date: | 2023-02-06 | Release date: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B 0 AT1 and ACE2-SIT1. Cell Discov, 9, 2023
|
|
1QSS
| DDGTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS | Descriptor: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3', ... | Authors: | Li, Y, Mitaxov, V, Waksman, G. | Deposit date: | 1999-06-23 | Release date: | 1999-08-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
1QH9
| ENZYME-PRODUCT COMPLEX OF L-2-HALOACID DEHALOGENASE | Descriptor: | 2-HALOACID DEHALOGENASE, LACTIC ACID | Authors: | Li, Y.-F, Hata, Y, Fujii, T, Kurihara, T, Esaki, N. | Deposit date: | 1999-05-12 | Release date: | 2000-05-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Structure of L-2-Haloacid Dehalogenase Complexed with a Reaction Product Reveals the Mechanism of Intermediate Hydrolysis in Dehalogenase To be Published
|
|
1QSY
| DDATP-Trapped closed ternary complex of the large fragment of DNA Polymerase I from thermus aquaticus | Descriptor: | 2',3'-dideoxyadenosine triphosphate, 5'-D(*AP*TP*TP*GP*CP*GP*CP*CP*TP*P*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3', ... | Authors: | Li, Y, Mitaxov, V, Waksman, G. | Deposit date: | 1999-06-24 | Release date: | 1999-08-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
1QTM
| DDTTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS | Descriptor: | 5'-D(*AP*AP*AP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DT))-3', DNA POLYMERASE I, ... | Authors: | Li, Y, Mitaxov, V, Waksman, G. | Deposit date: | 1999-06-28 | Release date: | 1999-08-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation. Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
5C2O
| Crystal structure of Streptococcus mutans Deoxycytidylate Deaminase complexed with dTTP | Descriptor: | MAGNESIUM ION, Putative deoxycytidylate deaminase, THYMIDINE-5'-TRIPHOSPHATE, ... | Authors: | Li, Y.H, Gao, Z.Q, Hou, H.F, Dong, Y.H. | Deposit date: | 2015-06-16 | Release date: | 2016-07-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Mechanism of the allosteric regulation of Streptococcus mutans 2'-deoxycytidylate deaminase. Acta Crystallogr D Struct Biol, 72, 2016
|
|
3C0F
| Crystal Structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source | Descriptor: | Uncharacterized protein AF_1514 | Authors: | Li, Y, Bahti, P, Shaw, N, Song, G, Yin, J, Zhu, J.-Y, Zhang, H, Xu, H, Wang, B.-C, Liu, Z.-J. | Deposit date: | 2008-01-20 | Release date: | 2008-02-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a novel non-Pfam protein AF1514 from Archeoglobus fulgidus DSM 4304 solved by S-SAD using a Cr X-ray source. Proteins, 71, 2008
|
|
8JA5
| Crystal structure of Nipah Virus attachment (G) glycoprotein in complex with neutralizing antibody 14F8 | Descriptor: | 14F8 antibody heavy chain, 14F8 antibody light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, Y.H, Huang, X.Y, Xu, J.J, Chen, W. | Deposit date: | 2023-05-05 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Crystal structure of Nipah Virus attachment (G) glycoprotein in complex with neutralizing antibody 14F8 To Be Published
|
|