7VDL
Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with circular cortistatin-14
Summary for 7VDL
Entry DOI | 10.2210/pdb7vdl/pdb |
EMDB information | 31922 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | g protein-coupled receptor, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 155808.18 |
Authors | |
Primary citation | Yang, F.,Guo, L.,Li, Y.,Wang, G.,Wang, J.,Zhang, C.,Fang, G.X.,Chen, X.,Liu, L.,Yan, X.,Liu, Q.,Qu, C.,Xu, Y.,Xiao, P.,Zhu, Z.,Li, Z.,Zhou, J.,Yu, X.,Gao, N.,Sun, J.P. Structure, function and pharmacology of human itch receptor complexes. Nature, 600:164-169, 2021 Cited by PubMed: 34789875DOI: 10.1038/s41586-021-04077-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.22 Å) |
Structure validation
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