7RX1
 
 | |
7S2Z
 | |
8V6T
 | | Crystal structure of EcThsB2 | | 分子名称: | BROMIDE ION, Molecular chaperone Tir | | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, E, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | | 登録日 | 2023-12-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems.
Sci Adv, 10, 2024
|
|
8V6R
 | | Crystal structure of EcThsA in complex with ADPR | | 分子名称: | Thoeris protein ThsA Macro domain-containing protein, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, E, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | | 登録日 | 2023-12-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems.
Sci Adv, 10, 2024
|
|
8V6S
 | | Crystal structure of PcThsA in complex with Imidazole Adenine Dinucleotide | | 分子名称: | Thoeris protein ThsA Macro domain-containing protein, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-imidazol-1-yl-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, E, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | | 登録日 | 2023-12-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems.
Sci Adv, 10, 2024
|
|
8V6Q
 | | Crystal structure of EcThsA in ligand-free state | | 分子名称: | Thoeris protein ThsA Macro domain-containing protein | | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, V, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | | 登録日 | 2023-12-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems.
Sci Adv, 10, 2024
|
|
5TEB
 | | Crystal Structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPP1 | | 分子名称: | Recognition of Peronospora parasitica 1 | | 著者 | Bentham, A.R, Zhang, X, Croll, T, Williams, S, Kobe, B. | | 登録日 | 2016-09-20 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.796 Å) | | 主引用文献 | Multiple functional self-association interfaces in plant TIR domains.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
7RTC
 | |
5D8C
 | | Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to promoter DNA | | 分子名称: | DNA (5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*GP*AP*AP*CP*TP*CP*TP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*TP*CP*AP*CP*TP*CP*TP*AP*AP*G)-3'), MerR family regulator protein | | 著者 | Counago, R.M, Chang, C.W, Chen, N.H, Djoko, K.Y, McEwan, A.G, Kobe, B. | | 登録日 | 2015-08-17 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region.
Nucleic Acids Res., 44, 2016
|
|
7NAK
 | | Cryo-EM structure of activated human SARM1 in complex with NMN and 1AD (TIR:1AD) | | 分子名称: | NAD(+) hydrolase SARM1, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(5-iodanylisoquinolin-2-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Kerry, P.S, Nanson, J.D, Adams, S, Cunnea, K, Bosanac, T, Kobe, B, Hughes, R.O, Ve, T. | | 登録日 | 2021-06-21 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules.
Mol.Cell, 82, 2022
|
|
7NAL
 | | Cryo-EM structure of activated human SARM1 in complex with NMN and 1AD (ARM and SAM domains) | | 分子名称: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, NAD(+) hydrolase SARM1 | | 著者 | Kerry, P.S, Nanson, J.D, Adams, S, Cunnea, K, Bosanac, T, Kobe, B, Hughes, R.O, Ve, T. | | 登録日 | 2021-06-21 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules.
Mol.Cell, 82, 2022
|
|
5V4L
 | |
5UZB
 | | Cryo-EM structure of the MAL TIR domain filament | | 分子名称: | Toll/interleukin-1 receptor domain-containing adapter protein | | 著者 | Ve, T, Vajjhala, P.R, Hedger, A, Croll, T, DiMaio, F, Horsefield, S, Yu, X, Lavrencic, P, Hassan, Z, Morgan, G.P, Mansell, A, Mobli, M, O'Carrol, A, Chauvin, B, Gambin, Y, Sierecki, E, Landsberg, M.J, Stacey, K.J, Egelman, E.H, Kobe, B. | | 登録日 | 2017-02-25 | | 公開日 | 2017-07-26 | | 最終更新日 | 2020-01-15 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling.
Nat. Struct. Mol. Biol., 24, 2017
|
|
6NSI
 | | Crystal structure of Fe(III)-bound YtgA from Chlamydia trachomatis | | 分子名称: | CALCIUM ION, FE (III) ION, Manganese-binding protein, ... | | 著者 | Luo, Z, Campbell, R, Begg, S.L, Kobe, B, McDevitt, C.A. | | 登録日 | 2019-01-24 | | 公開日 | 2019-10-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.00006342 Å) | | 主引用文献 | Structure and Metal Binding Properties of Chlamydia trachomatis YtgA.
J.Bacteriol., 202, 2019
|
|
7UXT
 | | Crystal structure of ligand-free SeThsA | | 分子名称: | GLYCEROL, TRIETHYLENE GLYCOL, USG protein | | 著者 | Shi, Y, Masic, V, Mosaiab, T, Nanson, J.D, Kobe, B, Ve, T. | | 登録日 | 2022-05-06 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling.
Science, 377, 2022
|
|
7MZO
 | | Crystal structure of the UcaD lectin-binding domain | | 分子名称: | CHLORIDE ION, Fimbrial adhesin UcaD | | 著者 | Ve, T, Lo, A.W, Schembri, M.A, Kobe, B. | | 登録日 | 2021-05-24 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli.
Plos Pathog., 18, 2022
|
|
7MZS
 | | Crystal structure of the UcaD lectin-binding domain in complex with galactose | | 分子名称: | CHLORIDE ION, Fimbrial adhesin UcaD, alpha-D-galactopyranose | | 著者 | Ve, T, Lo, A.W, Schembri, M.A, Kobe, B. | | 登録日 | 2021-05-24 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli.
Plos Pathog., 18, 2022
|
|
7MZQ
 | | Crystal structure of the UcaD lectin-binding domain in complex with fucose | | 分子名称: | CHLORIDE ION, Fimbrial adhesin UcaD, beta-L-fucopyranose | | 著者 | Ve, T, Lo, A.W, Schembri, M.A, Kobe, B. | | 登録日 | 2021-05-24 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli.
Plos Pathog., 18, 2022
|
|
7MZP
 | | Crystal structure of the UclD lectin-binding domain | | 分子名称: | F17-like fimbril adhesin subunit UclD, IODIDE ION | | 著者 | Ve, T, Lo, A.W, Schembri, M.A, Kobe, B. | | 登録日 | 2021-05-24 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli.
Plos Pathog., 18, 2022
|
|
7MZR
 | | Crystal structure of the UcaD lectin-binding domain in complex with glucose | | 分子名称: | CHLORIDE ION, Fimbrial adhesin UcaD, beta-D-glucopyranose | | 著者 | Ve, T, Lo, A.W, Schembri, M.A, Kobe, B. | | 登録日 | 2021-05-24 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli.
Plos Pathog., 18, 2022
|
|
7M6K
 | |
6O0W
 | | Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1 in complex with NADP+ and Bis-Tris | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-2'-5'-DIPHOSPHATE, TIR-NB-LRR type resistance protein RUN1 | | 著者 | Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B. | | 登録日 | 2019-02-17 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
|
|
7JJ9
 | | Crystal structure of Zn(II)-bound AdcA from Streptococcus pneumoniae | | 分子名称: | CHLORIDE ION, ZINC ION, Zinc-binding lipoprotein AdcA | | 著者 | Luo, Z, More, J.R, Kobe, B, McDevitt, C.A. | | 登録日 | 2020-07-24 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA.
Mbio, 12, 2021
|
|
7JJB
 | | Crystal structure of Zn(II)-bound ZinT-like domain of Streptococcus pneumoniae AdcA | | 分子名称: | MAGNESIUM ION, SODIUM ION, ZINC ION, ... | | 著者 | Luo, Z, More, J.R, Kobe, B, McDevitt, C.A. | | 登録日 | 2020-07-24 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA.
Mbio, 12, 2021
|
|
7JJA
 | | Crystal structure of the ZinT-like domain of Streptococcus pneumoniae AdcA in the apo form | | 分子名称: | SODIUM ION, Zinc-binding lipoprotein AdcA, {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID | | 著者 | Luo, Z, More, J.R, Kobe, B, McDevitt, C.A. | | 登録日 | 2020-07-24 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.01 Å) | | 主引用文献 | A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA.
Mbio, 12, 2021
|
|
