5D8C

Crystal structure of HiNmlR, a MerR family regulator lacking the sensor domain, bound to promoter DNA

Summary for 5D8C

• Entry DOI: 10.2210/pdb5d8c/pdb
• Descriptor: MerR family regulator protein, DNA (5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*TP*CP*AP*CP*TP*CP*TP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*AP*GP*AP*GP*TP*GP*AP*AP*CP*TP*CP*TP*AP*AP*G)-3'), ... (4 entities in total)
• Functional Keywords: transcription factor, merr, thiol-based genetic switch, dna untwisting, transcription-dna complex, transcription/dna
• Biological source: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd); More
• Total number of polymer chains: 4
• Total formula weight: 42404.27

Authors

Counago, R.M.,Chang, C.W.,Chen, N.H.,Djoko, K.Y.,McEwan, A.G.,Kobe, B. (deposition date: 2015-08-17, release date: 2016-06-29, Last modification date: 2023-09-27)

• Primary citation: Counago, R.M.,Chen, N.H.,Chang, C.W.,Djoko, K.Y.,McEwan, A.G.,Kobe, B.; Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region.; Nucleic Acids Res., 44:6981-6993, 2016; PubMed: 27307602; DOI: 10.1093/nar/gkw543

Experimental method

X-RAY DIFFRACTION (2.25 Å)