7S2Z

Crystal structure of the E100A mutant TIR domain from the grapevine disease resistance protein RUN1 bound to NAD

Summary for 7S2Z

• Entry DOI: 10.2210/pdb7s2z/pdb
• Descriptor: Disease resistance protein RUN1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: nad+ hydrolase, signalling protein, tir domain, nad+ nucleosidase activity, signaling protein, hydrolase
• Biological source: Vitis rotundifolia (Muscadine grape)
• Total number of polymer chains: 4
• Total formula weight: 87004.22

Authors

Burdett, H.,Kobe, B. (deposition date: 2021-09-04, release date: 2021-10-13, Last modification date: 2024-11-13)

• Primary citation: Burdett, H.,Hu, X.,Rank, M.X.,Maruta, N.,Kobe, B.; Self-association configures the NAD + -binding site of plant NLR TIR domains; Biorxiv, 2021; DOI: 10.1101/2021.10.02.462850

Experimental method

X-RAY DIFFRACTION (2.35 Å)