7S2Z
Crystal structure of the E100A mutant TIR domain from the grapevine disease resistance protein RUN1 bound to NAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Disease resistance protein RUN1 | polymer | 179 | 20655.3 | 4 | UniProt (V9M398) | Vitis rotundifolia (Muscadine grape) | NAD(+) hydrolase RUN1,NADP(+) hydrolase RUN1,Resistance to Uncinula necator protein,MrRUN1 |
| 2 | E, K, Q, V (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, G, H, I, J... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 18 | Chemie (SO4) | |||
| 4 | AA, BA, CA, DA (A, B, C, D) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 23 - 198 (UniProt: V9M398)
| PDB | External Database | Details |
|---|---|---|
| Ser 20 | - | expression tag |
| Asn 21 | - | expression tag |
| Ala 22 | - | expression tag |
| Ala 100 | Glu 100 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 82621.4 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 4382.8 | |
| All* | Total formula weight | 87004.2 |
